Christian McCaffrey will lead the San Francisco 49ers (5-2) into their game against the Houston Texans (2-4) at NRG Stadium on Sunday at 1 p.m. ET.
In terms of points scored the 49ers rank 23rd in the NFL (20.7 points per game), and they are seventh defensively (19.7 points allowed per game). The Texans rank 22nd in total offense this season (304.3 yards per game), but they’ve been shining on the other side of the ball, ranking fourth-best in the NFL with 304.3 yards allowed per game.
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49ers vs Texans: Live streaming info, TV channel & game timeGame day: Sunday, October 26, 2025Game time: 1 p.m. ETLocation: Houston, TexasStadium: NRG StadiumTV channel: FOXLive stream: Watch on Fubo! (Regional restrictions may apply)
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49ers vs Texans betting lines
NFL odds courtesy of BetMGM. Odds updated Sunday at 12:29 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Texans (-2.5)Moneyline: Texans (-133), 49ers (+112)Total: 42 points
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