For the first time in a long time, Bank of America Stadium is playing host to a big-time game.
On Sunday, the 4-3 Carolina Panthers will welcome in the 4-2 Buffalo Bills—one of this season’s top Super Bowl favorites. And even although head coach Sean McDermott and company head in with the league’s reigning Most Valuable Player and real aspirations for the Lombardi Trophy, the home team ain’t too shabby of late either.
Can the Panthers add to their three-game winning streak?
Do they have what it takes, especially without their starting quarterback Bryce Young, to pull of an eye-opening upset?
Here’s how you can tune in to find out . . .
Stream Panthers vs. Bills (free trial)
What channel is Panthers vs. Bills game on today?TV channel: FOXStreaming: NFL Sunday Ticket (YouTube) | Fubo (free trial)
Panthers vs. Bills will broadcast on FOX (in the orange areas of the map) in Week 8 of the 2025 season. Adam Amin (play-by-play commentator), Greg Olsen (color analyst) and Pam Oliver (sideline reporter) are on the call.
Streaming options for the game include NFL Sunday Ticket on YouTube, FOX’s streaming service and Fubo, which offers a free trial to new subscribers.
Panthers vs. Bills time todayDate: Sunday, Oct. 26, 2025Time: 1:00 p.m. ET
Panthers vs. Bills will kick off on Sunday, Oct. 26 at 1:00 p.m. ET from Bank of America Stadium in Charlotte, N.C.
Panthers vs. Bills predictions, picks, oddsPicks: Click here for expert predictions for Panthers vs. BillsSpread: Bills -7Over/under: 46Moneyline: Panthers +305, Bills -390
Odds courtesy of BetMGM as of Saturday, Oct. 25 (12:00 A.M. ET)
Panthers 2025 regular-season scheduleWeek 1: at Jacksonville Jaguars (Loss, 26-10)Week 2: at Arizona Cardinals (Loss, 27-22)Week 3: vs. Atlanta Falcons (Win, 30-0)Week 4: at New England Patriots (Loss, 42-13)Week 5: vs. Miami Dolphins (Win, 27-24)Week 6: vs. Dallas Cowboys (Win, 30-27)Week 7: at New York Jets (Win, 13-6)Week 8: vs. Buffalo Bills (Sunday, Oct. 26 at 1:00 p.m. ET)Week 9: at Green Bay Packers (Sunday, Nov. 2 at 1:00 p.m. ET)Week 10: vs. New Orleans Saints (Sunday, Nov. 9 at 1:00 p.m. ET)Week 11: at Atlanta Falcons (Sunday, Nov. 16 at 1:00 p.m. ET)Week 12: at San Francisco 49ers (Monday, Nov. 24, 8:15 p.m. ET)Week 13: vs. Los Angeles Rams (Sunday, Nov. 30 at 1:00 p.m. ET)Week 14: ByeWeek 15: at New Orleans Saints (Sunday, Dec. 14 at 4:25 p.m. ET)Week 16: vs. Tampa Bay Buccaneers (Sunday, Dec. 21 at 1:00 p.m. ET)Week 17: vs. Seattle Seahawks (TBD)Week 18: at Tampa Bay Buccaneers (TBD)
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