On Sunday, November 2, 2025 at Nissan Stadium, the Tennessee Titans (1-7) have an expected tough battle to end their three-game losing streak as they are 9.5-point underdogs against the Los Angeles Chargers (5-3). For this game, an over/under of 43.5 has been set.

Looking to make a parlay bet on this game? See insights, including first to score and player prop bet insights, below in this article.

Chargers vs. Titans game odds

NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 7:41 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread: Chargers -9.5 (-110 to cover)Moneylines: Chargers -500, Titans +375Total: 43.5 points (Over: -110, Under: -110)Pick ATS: Titans (+9.5)Pick OU: Over (43.5)Prediction:
Chargers 26 – Titans 18First TD odds and insights

First TD odds: Chargers -235, Titans +175

The Chargers have scored the opening touchdown five times in eight games.In those five games, one of Los Angeles’ scores came rushing the ball, and four in the air.In the first quarter, the Chargers have scored four touchdowns, 13th in the league.The Titans have scored the opening touchdown in one of eight games this year.Of Tennessee’s one first TD, each came on a passing play.In the first quarter, the Titans have scored one touchdown, 30th in the NFL.

Watch Los Angeles Chargers vs. Tennessee Titans on Fubo!

Justin Herbert player propsPassing yard prop: Over/under 242.5 yardsRushing yard prop: Over/under 15.5 yardsCompared to his 242.5-yard over/under for this matchup, Justin Herbert is putting up more yards per game (267.5) so far this season.Keenan Allen player propsReceiving yard prop: Over/under 46.5 yardsKeenan Allen’s 59.9 receiving yards per game are 13.4 more than his prop bet over/under for Sunday’s game (46.5).Cameron Ward player propsPassing yard prop: Over/under 206.5 yardsRushing yard prop: Over/under 4.5 yardsCameron Ward throws for 201.9 passing yards per game this season, which is less than his prop bet total for this matchup of 206.5.Tony Pollard player propsRushing yard prop: Over/under 36.5 yardsReceiving yard prop: Over/under 14.5 yardsTony Pollard’s 53 rushing yards per game average is 16.5 greater than Sunday’s over/under.