As we enter the double-digit weeks of the fantasy season, the stage is set for the contenders to rise and the pretenders to fall. Every team has weathered its share of triumphs and setbacks, and now every decision carries added weight. The margin for error has evaporated, and each waiver claim, trade, or lineup adjustment could determine the difference between survival and collapse. This is crunch time, when strategy meets resolve, and only those who stay sharp in their pursuit of championship glory will endure. With the trade deadline set for 4 p.m. ET on Tuesday, several situations could shift quickly, so keep a close eye on any late moves. With that in mind, here are the top pickups to help guide you to victory in Week 10.
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Dylan Sampson, RB, Cleveland Browns – Rookie sensation Quinshon Judkins exited Week 8 with a shoulder injury that, while not believed to be serious, could still sideline him for a short stretch. Should Judkins miss time, fellow rookie Dylan Sampson is expected to take over as Cleveland’s lead back. Though Sampson was limited to just three carries for no gain in the Week 8 loss to New England, he made his mark in the passing game by catching five of six targets for 29 yards. Jerome Ford, meanwhile, was barely involved, touching the ball only twice. With the Browns coming off their bye, there is a chance that Judkins could return right away. However, if he is held out, Sampson profiles as a sneaky start in a favorable Week 10 matchup against the Jets.
Isaiah Davis, RB, New York Jets – After opening the season 0-7, the New York Jets shocked the league with a stunning Week 8 upset over the Bengals. Isaiah Davis played a key role in the victory, rushing seven times for 65 yards and catching all five of his targets for 44 more. With Breece Hall coming into the game banged up, Davis saw an expanded workload and made the most of his opportunity.
Coming out of their bye week, the Jets may look to keep Davis more involved, especially if Hall’s health remains a concern. That potential for an increased role makes Davis an intriguing flex option in the right game scripts. If trade rumors surrounding Hall turn into reality before the deadline, Davis could suddenly find himself atop the depth chart. His combination of burst and versatility makes him a high-upside speculative add heading into a tough Week 10 matchup against the Browns. Should Hall be traded, Davis would instantly emerge as the most coveted pickup of the week.

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Devin Singletary, RB, New York Giants – After Cam Skattebo’s season-ending ankle injury, New York was expected to feature Tyrone Tracy in the backfield. Instead, it was veteran Devin Singletary who proved more effective in Week 9. He led the team with eight carries for 43 yards and added two catches for eight yards in the loss to San Francisco. While this backfield looks headed for a timeshare, Singletary’s efficiency and role should not be overlooked. He is worth a pickup and could offer flex appeal heading into a favorable Week 10 matchup with the Bears.
Blake Corum, RB, Los Angeles Rams – After a quiet rookie year, Blake Corum is starting to show glimpses of the talent that made him such a coveted prospect out of Michigan. In Week 9’s win over the Saints, he carried 13 times for 58 yards, flashing the burst and creativity that defined his college career. He has now logged double-digit carries in back-to-back games and has settled into a clear complementary role behind Kyren Williams. That gives him some desperation flex value for now, but more importantly, he is one of the top handcuffs in fantasy football. If Williams were to miss time, Corum has the skill set and opportunity to become a league-altering player down the stretch.
Bhayshul Tuten, RB, Jacksonville Jaguars – It has not been the rookie breakout many envisioned heading into the season, but Bhayshul Tuten’s role in Jacksonville’s backfield continues to grow. Coming out of the bye, he saw his busiest game of the season in Sunday’s win over the Raiders, rushing nine times for 29 yards and a score. Travis Etienne remains firmly in control of the backfield and did nothing to loosen that grip, but Tuten’s involvement is trending up. His workload could soon reach a point where he becomes fantasy relevant even with both backs active. More importantly, if Etienne were to miss time, Tuten has the skill set to emerge as a potential league-winner. He is an intriguing stash as Jacksonville heads into a daunting Week 10 matchup with Houston.
Terrell Jennings, RB, New England Patriots – When news broke that Rhamondre Stevenson would miss Week 9 with a toe injury, most expected second-round pick TreVeyon Henderson to dominate the backfield work. While Henderson did lead the team in opportunities and looked sharp as the lead back, Terrell Jennings carved out a meaningful role in Sunday’s win over Atlanta. Jennings rushed 11 times for 35 yards and a TD and added a nine-yard reception. In a high-scoring offense, having the goal-line role gives him legitimate fantasy upside while Stevenson remains sidelined, even if Henderson continues to see more touches. With Stevenson’s return timeline uncertain and the possibility of a backfield addition still on the table, Jennings is an intriguing speculative add ahead of New England’s Week 10 matchup with Tampa Bay.
Emari Demercado, RB, Arizona Cardinals – Trying to predict who will lead Arizona’s backfield has turned into a weekly headache. Just when it looked like Bam Knight had secured the job, Emari Demercado stole the spotlight in Monday night’s win against the Cowboys. He racked up 79 yards on 14 carries and came through late when the team needed him most. It is anyone’s guess who will headline the backfield next week, but Demercado’s performance deserves attention as he looks to carry that momentum into a tough Week 10 matchup with Seattle.
Alec Pierce, WR, Indianapolis Colts – What more does this man have to do to earn some respect? After a quiet season opener, Alec Pierce has been a startable option in nearly every game since. His combination of size and speed makes him an ideal deep threat for Daniel Jones, but in recent weeks, he has proven to be much more than that. Pierce has seen double-digit targets in two of his last three games, including a season-best performance in Sunday’s loss to the Steelers, when he caught six of 13 targets for 115 yards. He still has not found the end zone this year, but that feels imminent, and a TD would unlock another level to his fantasy ceiling. Pierce should be rostered in all leagues and can be confidently started as the Colts look to rebound against the Falcons in Week 10 before their bye.
Parker Washington, WR, Jacksonville Jaguars – After a quiet start to his third NFL season, Parker Washington has come alive over the past two weeks. He saw 10 targets in Week 7 before Jacksonville’s bye and returned to action as a top option for Trevor Lawrence, catching eight of nine targets for 90 yards. With Travis Hunter already on IR and Brian Thomas Jr. leaving Sunday’s game with an ankle injury, Washington might be positioned as the WR1 in this offense moving forward. He should continue to see a heavy target share, making him a top waiver pickup this week, even with a challenging matchup against the Texans in Week 10.

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Christian Watson, WR, Green Bay Packers – Green Bay’s WR group has been inconsistent all season, and things took another hit when star TE Tucker Kraft suffered a season-ending injury. In Sunday’s disappointing loss to the Panthers, Christian Watson caught two of four targets for 58 yards, following up a strong Week 8 performance where he hauled in four passes for 85 yards. Watson remains the team’s premier deep threat and should see an expanded role with Kraft sidelined. He is a strong pickup this week, even if his Week 10 matchup against Philadelphia’s secondary could limit his ceiling.
Darius Slayton, WR, New York Giants – Even in defeat, Jaxson Dart continues to show poise and progress in his rookie season. One development flying under the radar is his growing chemistry with Darius Slayton. The two have narrowly missed connecting on several big plays in recent weeks, some wiped out by penalties and others by drops that could just as easily go the other way. In Sunday’s loss to the 49ers, Slayton turned in his best outing of the year, catching five of seven targets for 62 yards. He is quickly becoming Dart’s go-to option, and that connection could lead to bigger results soon. With a favorable Week 10 matchup against the Bears on deck, Slayton emerges as an intriguing pickup and play.
Tory Horton, WR, Seattle Seahawks – “T” as in Troy? No, Gabriella, “T” as in Tory Horton had two TDs on Monday Night Football! Horton had already flashed his potential earlier in the season with three scores entering Week 9, but Monday marked his best performance yet. He caught all four of his targets for 48 yards and two TDs, capitalizing on the absence of Cooper Kupp and a flawless first half from Sam Darnold. While Jaxon Smith-Njigba remains the clear alpha in this offense, Horton looks like a rookie on the rise who could carve out consistent production in the second half of the season. He is still a bit boom-or-bust, but he stands out as an intriguing stash as he looks to stay hot in a Week 10 matchup against Arizona.
Demario Douglas, WR, New England Patriots – Any time a player posts 100 receiving yards and a TD, they deserve recognition. In Sunday’s win over the Falcons, Douglas delivered that exact stat line on just four catches, stepping up for his team in a big way. He took advantage of Kayshon Boutte leaving the game with a hamstring injury and seamlessly filled the role. Boutte’s availability moving forward remains uncertain, but if he misses time, Douglas could see an expanded workload and a chance for another productive outing against Tampa Bay in Week 10.
Colston Loveland, TE, Chicago Bears – Catson Loveland? Kitten Loveland? Mr. Bigglesworth? None of the above. Colston Loveland proved in Week 9 that he’s got that dawg in him. The rookie erupted for 118 yards on six catches, including a 58-yard game-winning TD where he broke tackles and showed off his elite speed to seal the victory. While the matchup against the Bengals was favorable, this performance felt like a genuine breakout for the first-round pick. With Cole Kmet leaving early due to a concussion, Loveland is positioned to build on his momentum and should be the top waiver add at the position. He can be picked up and confidently started in another strong matchup against the Giants in Week 10.
Harold Fannin Jr., TE, Cleveland Browns – Harold Fannin Jr. sits just above the 60% rostered threshold, but he is still available in far too many leagues. In Week 8, he caught six of eight targets for 62 yards and has quietly been one of the few bright spots in Cleveland’s struggling offense. He has become a steady and trusted option for their rookie QB, and coming out of the bye, his role could grow even further. If he is still on your waiver wire, do not hesitate. Fannin can be picked up and started right away in a favorable Week 10 matchup against the Jets.
Check out Javier Manzanera’s weekly article on QB Streamers to Consider.
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Final Thoughts
As the single-digit weeks come to a close, the road ahead grows shorter and every opportunity more precious. The easy wins are gone, and from here on out, success belongs to those who adapt quickly and refuse to back down. Whether you are fighting for a playoff spot or strengthening your roster for the final push, every move counts. Stay calculated, stay resilient, and keep your eyes on the ultimate prize of championship glory. Good luck in Week 10, and I will see you on the other side as we regroup and build momentum for the playoff push.