For Sunday’s game, which kicks off at 4:25 p.m. ET on FOX, bookmakers have installed player prop bet markets on Christian McCaffrey. NFC West rivals square off in Week 10 when McCaffrey and the San Francisco 49ers (6-3) meet the Los Angeles Rams (6-2) at Levi’s Stadium.

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Christian McCaffrey week 10 player propsMatchup: San Francisco 49ers vs. Los Angeles RamsTime: 4:25 p.m. ETDate: November 9, 2025Rushing yards prop: Over 67.5 (-115)Receiving yards prop: Over 50.5 (-115)

National Football League odds courtesy of BetMGM. Odds updated Wednesday at 9:47 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Christian McCaffrey rushing stats and trendsMcCaffrey collects 66.2 rushing yards per game this season, 1.3 less than Sunday’s prop total.In 33.3% of his games (three of nine matchups) so far, he has rushed for more than 67.5 yards.McCaffrey’s average rushing yards over/under so far this season (67.8) is just a bit higher than his rushing yard average (66.2) this year.McCaffrey hit the over on his rushing yards prop bet total in three of his nine opportunities this year (33.3%).He had multiple rushing TDs in one game this year, while scoring in three games.49ers vs. Rams stats and trendsMcCaffrey will go up against a Rams squad that allows 99.8 rushing yards per game and is the NFL’s 11th-ranked rush defense.The Rams have the NFL’s 13th-ranked pass defense this season, allowing 203.1 yards per game through the air.The 49ers rank 20th in pass defense this year (223.7 passing yards allowed per game), but they’ve been playing really well on the other side of the ball, ranking fifth-best in the NFL with 255.0 passing yards per game.The 49ers are putting up 97.1 rushing yards per game on offense this season (26th in NFL), and they are allowing 108.9 rushing yards per game (15th) on defense.The 49ers are allowing 5.6 yards per play on the defensive side of the ball (15th in the NFL), while putting up 5.6 per play (14th in the league) on offense this season.

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