The AFC West spotlight turns to Denver on Thursday night as the Broncos host the Las Vegas Raiders under the lights at Mile High. Denver enters as a 9.5-point favorite after a resurgent stretch has put them back in the Wild Card conversation, while Las Vegas looks to spoil the party and snap its skid against a division rival. The Dimers model gives the Broncos a 78% chance to win, but the Raiders’ offense—led by Geno Smith, Brock Bowers, and rookie back Ashton Jeanty—has shown enough flashes to make this primetime matchup more interesting than the spread suggests.

Kickoff is set for 8:15 p.m. ET, with the total listed at 42.5 points. Dimers projects a 25–17 Broncos victory, though the Raiders moneyline (+410) offers sneaky betting value based on model edge. Expect a grind-it-out game at altitude, where J.K. Dobbins and Courtland Sutton headline Denver’s attack while Las Vegas looks to find rhythm early and keep the crowd quiet. It’s a classic AFC West clash—high stakes, unpredictable, and likely decided in the trenches.

Raiders vs. Broncos betting preview

Utilize the interactive widget below to see the latest spread, total, and moneyline odds and probabilities for the Raiders-Broncos matchup at Empower Field at Mile High.

This prediction and best bet for Thursday’s NFL matchup between the Raiders and Broncos is from Dimers.com, a reliable source for sports betting predictions.

Check out all the important details on today’s game, as well as the best odds sourced from the top sportsbooks in the country.

Game details

Key information on the Raiders vs. Broncos matchup, including where the game is and what time it kicks off.

Teams: Las Vegas Raiders vs. Denver BroncosDate: Thursday, November 6, 2025Kickoff: 8:15 p.m. ESTLocation: Empower Field at Mile HighNFL standings: Current NFL division standingsNFL injuries: Check the latest updates to the official NFL injury reportOdds

The latest and best odds for the NFL battle between the Raiders and Broncos.

Spread: Raiders +9.5 (-110), Broncos -9.5 (-110)Moneyline: Raiders +410, Broncos -475Total: Over/Under 42.5 (-112/-102)

The odds and lines featured here are the best available from selected sports betting sites at the time of publication and are subject to change.

Expert prediction: Raiders vs. Broncos

Utilizing cutting-edge data analysis and advanced algorithms, the experts at Dimers have performed 10,000 simulations of Thursday’s Raiders vs. Broncos game.

According to Dimers’ popular predictive analytics model, the Broncos are more likely to beat the Raiders at Empower Field at Mile High. This prediction is based on the model giving the Broncos a 78% chance of winning the game.

Furthermore, Dimers predicts that the Raiders (+9.5) have a 55% chance of covering the spread, while the over/under total of 42.5 points is considered an equal 50-50 chance of hitting.

These predictions and probabilities are correct at the time of publication but are subject to potential changes.

Raiders vs. Broncos best bet

Our top pick for the Raiders vs. Broncos Week 10 NFL game is to bet on the Raiders moneyline (+410).

This expert betting advice is based on world-class simulations and valuable betting intelligence, designed to assist you in making smarter investments.

While the Broncos are more likely to win the game, according to Dimers, taking the Raiders moneyline is the best option due to the 2.4% edge found when comparing Dimers’ data-driven probabilities to the betting odds.

Score prediction for Raiders vs. Broncos

Dimers’ projected final score for the Las Vegas vs. Denver game on Thursday has the Broncos winning 25-17.

This expert prediction is based on each team’s average score following 10,000 game simulations, offering a glimpse into the potential outcome.

NFL player props: Thursday

NFL player prop bets are an enjoyable way to wager on Thursday’s game without necessarily betting on its outcome.

This article features the most likely first and anytime touchdown scorers for the Raiders and Broncos, as well as projected player stats.

Las Vegas RaidersFirst touchdown scorer predictionsAshton Jeanty: 12.0% probabilityBrock Bowers: 8.1% probabilityTre Tucker: 5.0% probabilityAnytime touchdown predictionsAshton Jeanty: 46.9% probabilityBrock Bowers: 34.8% probabilityTre Tucker: 23.2% probabilityProjected box score leadersQB passing yards: Geno Smith, 214 yardsReceiving yards: Brock Bowers, 65 yardsRushing yards: Ashton Jeanty, 57 yardsDenver BroncosFirst touchdown scorer predictionsJ.K. Dobbins: 12.2% probabilityCourtland Sutton: 8.6% probabilityTroy Franklin: 7.2% probabilityAnytime touchdown predictionsJ.K. Dobbins: 47.0% probabilityCourtland Sutton: 36.3% probabilityTroy Franklin: 31.3% probabilityProjected box score leadersQB passing yards: Bo Nix, 229 yardsReceiving yards: Courtland Sutton, 62 yardsRushing yards: J.K. Dobbins, 73 yardsNFL Week 10: Raiders vs. Broncos

Get ready for Thursday’s game between the Raiders and Broncos in Week 10 of the National Football League season at Empower Field at Mile High, which is scheduled to start at 8:15 p.m. EST. We emphasize that all of the NFL best bets and NFL predictions in this article are based on 10,000 data-driven simulations of the Raiders vs. Broncos matchup, and they are correct at the time of publishing to help you make more informed choices when placing bets at online sportsbooks.

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