The Seattle Seahawks (6-2) are favored by 6.5 points as they try to keep their three-game winning streak going in a matchup with the Arizona Cardinals (3-5) on Sunday, November 9, 2025 at Lumen Field.

Seahawks vs. Cardinals game infoGame day: Sunday, November 9, 2025Game time: 4:05 p.m. ETTV channel: CBSLocation: Seattle, WashingtonStadium: Lumen FieldLive stream: Watch this game on Fubo (Regional restrictions may apply)Live stream: Watch this game on Paramount+ (Regional restrictions may apply)

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Seahawks vs. Cardinals odds & betting linesSpread favorite: Seattle (-6.5)Moneyline: Seattle (-318), Arizona (+255)Total: 45 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Seahawks vs. Cardinals recent matchupsSeattle has gone 5-0 versus Arizona over the last five matchups between the two teams.In those games versus the Cardinals, the Seahawks have gone 4-1 against the spread, with those games outscoring the point total on one occasion.Seattle outscored Arizona 110-74 in those five head-to-head matchups.Seahawks vs. Cardinals betting insightsSeattle is 6-2-0 against the spread this season. In the six games this season the Seahawks have been favored on the moneyline, they have put together a 5-1 record. Arizona has a 5-3-0 record against the spread this season. The Cardinals’ record is 1-4 when playing as the underdog this year.Seahawks scoring insightsThe Seahawks are averaging more points at home (29.8) than on the road (28.0).Defensively, Seattle’s average at home, 21.8 points conceded, is worse than its average away, 15.8.The Seahawks’ defense has been creating chaos for opposing offenses over the last three games, ranking fourth-best by surrendering only 15.0 points per game. On offense, they rank eighth in the NFL over that three-game stretch (28.3 points per game).Cardinals scoring insightsAt home, the Cardinals’ scoring average is 22.8 points per game, which is slightly higher than their average on the road, 22.3.Defensively, Arizona is giving up 23.5 points per game at home, worse than its 19.3 average on the road.In terms of points scored, including the past three games only, the Cardinals are 14th in the NFL (25.7 per game). On the other side of the ball they are 20th in points conceded (25.0).Seahawks injury reportSeahawks:
Dareke Young: Did Not Participate In Practice (Quadricep),
Jarran Reed: Full Participation in Practice (Wrist),
Cooper Kupp: Limited Participation in Practice (Hamstring),
Ernest Jones: Limited Participation in Practice (Knee),
Josh Jobe: Did Not Participate In Practice (Concussion),
Tory Horton: Did Not Participate In Practice (Groin),
Christian Haynes: Full Participation in Practice (Pectoral),
Jake Bobo: Did Not Participate In Practice (Calf),
AJ Barner: Limited Participation in Practice (Calf),
Elijah Arroyo: Full Participation in Practice (Elbow)Cardinals injury reportCardinals:
Will Johnson: Did Not Participate In Practice (Back),
Xavier Weaver: Limited Participation in Practice (Ankle),
BJ Ojulari: Limited Participation in Practice (Knee),
Zay Jones: Limited Participation in Practice (Knee),
Will Hernandez: Limited Participation in Practice (Knee),
Kitan Crawford: Limited Participation in Practice (Hamstring),
Kei’Trel Clark: Limited Participation in Practice (Ankle),
Budda Baker: Limited Participation in Practice (Hamstring),
Mack Wilson: Did Not Participate In Practice (Ribs),
Max Melton: Did Not Participate In Practice (Concussion),
Kelvin Beachum: Full Participation in Practice (Rest)

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