The New York Giants (2-7) and Chicago Bears (5-3) meet Sunday afternoon for a Week 10 battle from Soldier Field in Chicago, Illinois. Kickoff is set for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Giants vs. Bears odds and make our expert NFL picks and predictions for the best bets.

The Giants suffered their third straight defeat Sunday, losing 34-24 to the San Francisco 49ers as a 2.5-point home underdog as the Over (47) cashed. New York has performed well offensively, but has had significant defensive issues, allowing 33 points or more in 3 straight contests. It is 4-5 against the spread (ATS) and 5-4 O/U.

The Bears took down the Cincinnati Bengals in a shootout Sunday, winning 47-42 and covering as a 3-point road favorite as the Over (51) cleared with ease. The Bears ended with 576 total yards, 283 of which were on the ground. QB Caleb Williams played a near-perfect game with 280 yards and 3 TDs. After losing its first 2 games, Chicago has won 5 of its last 6 contests.

The Giants beat the Bears 20-12 and covered as a 3-point favorite at home as the Under (39) hit on Oct. 2, 2022, the last time these teams met. The Bears lead the all-time series 36-25-2, including 8 postseason games. 

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Giants at Bears odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 6:49 p.m. ET.

Moneyline (ML): Giants +180 (bet $100 to win $180) | Bears -220 (bet $220 to win $100)Against the spread (ATS): Giants +4.5 (-110) | Bears -4.5 (-110)Over/Under (O/U): 46.5 (O: -110 | U: -110)Giants at Bears key injuries

Giants

CB Paulson Adebo (knee) outWR Beaux Collins (neck) outG Jermaine Eluemunor (pec) questionableS Jevon Holland (knee) questionableLB Darius Muasau (ankle) outC John Michael Schmitz (shin) out

Bears

LB T.J. Edwards (hand/hamstring) outDL Dominique Robinson (ankle) outRB D’Andre Swift (groin/non-injury related) questionableGiants at Bears picks and predictionsPrediction

Bears 30, Giants 21

PASS.

The Bears (-220) should come out on top, but are too expensive to consider.

BET BEARS -4.5 (-110).

The Bears have been surging over the last month and a half. They are 5-1 ATS in their last 6 games and 3-2 ATS at home on the season. Chicago has scored at least 25 points in 5 of its last 6 games, so it should score enough to pull away in this one.

The Giants are allowing 31.6 points per game on the road and are 2-3 ATS in those contests. With a few banged-up offensive lineman, a team that already ranks in the bottom third of sack percentage may struggle to keep QB Jaxson Dart upright.

BET OVER 46.5 (-110).

Both teams have shown consistency offensively, but not defensively. The Bears are 5-3 O/U on the season and have allowed at least 24 points in 4 of their last 5 games. Their defense ranks 29th (70.95%) in opponents’ completion percentage.

The Giants are 5-4 O/U and have gone Over the projected total in 4 straight games. They have tallied at least 24 points in 3 of those contests. Back OVER 46.5 (-110).

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