PHOENIX (AZFamily) — The Arizona Cardinals will be without a major piece of their offense this weekend.
Wide receiver Marvin Harrison Jr. had surgery for appendicitis on Monday night and will miss Sunday’s game against the San Francisco 49ers, the team confirmed on Wednesday.
Harrison caught a second-half touchdown in the Cardinals’ defeat to the Seattle Seahawks last week.
Arizona Cardinals wide receiver Marvin Harrison Jr. makes a touchdown catch against the Seattle Seahawks during an NFL football game Sunday, Nov. 9, 2025, in Seattle. (AP Photo/Lindsey Wasson)(Lindsey Wasson | AP)
Quarterback Kyler Murray was moved to the Injured Reserve last week. But after Sunday’s debacle, the quarterback position is just one of many problems facing Arizona.
The Cardinals were beaten up against the Seahawks, with defensive linemen Darius Robinson (groin) and Walter Nolen III (knee), running back Bam Knight (ankle), receivers Zay Jones (Achilles) and Simi Fehoko (arm), safety Dadrion Taylor-Demerson (ankle) and right tackle Jonah Williams (shoulder) all leaving with injuries.
The Associated Press contributed to this report.
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