Check out these betting insights before you place player prop wagers on Christian McCaffrey for Sunday’s game, which starts at 4:05 p.m. ET on FOX. NFC West rivals play in Week 11 when McCaffrey and the San Francisco 49ers (6-4) meet the Arizona Cardinals (3-6) at State Farm Stadium.
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Christian McCaffrey week 11 player propsMatchup: San Francisco 49ers at Arizona CardinalsTime: 4:05 p.m. ETDate: November 16, 2025Rushing yards prop: Over 71.5 (-111)Receiving yards prop: Over 51.5 (-111)
National Football League odds courtesy of BetMGM. Odds updated Thursday at 5:47 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Christian McCaffrey rushing stats and trendsMcCaffrey averages 62.6 rushing yards per game average in 2025, 8.9 less than Sunday’s over/under.He has totaled more than 71.5 rushing yards in a game twice this season.McCaffrey gains 5.0 fewer yards per game this season than his average rushing yards prop (67.6 yards).McCaffrey went over on his rushing yards prop bet total in three of his 10 opportunities this year (30.0%).He recorded multiple rushing touchdowns in one game this year, while scoring in three games.49ers vs. Cardinals stats and trendsConceding 114.1 rushing yards per game, the Cardinals have the 18th-ranked run defense in the NFL.The Cardinals are allowing 225.3 passing yards per game this year, the NFL’s 20th-ranked pass defense.The 49ers rank 22nd in pass defense this season (228.8 passing yards allowed per game), but they’ve been thriving on offense, ranking best in the NFL with 261.4 passing yards per game.From an offensive standpoint, the 49ers rank 27th in the NFL with 94.8 rushing yards per game. Meanwhile, they rank 16th in rushing yards allowed per contest (110.6).The 49ers are averaging 5.7 yards per play on offense, which ranks them 14th in the NFL. Defensively, they rank 15th, giving up 5.6 yards per play.
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