A pair of the top offensive performers in the NFL will be featured when James Cook and the Buffalo Bills (6-3) host Emeka Egbuka and the Tampa Bay Buccaneers (6-3) on Sunday, November 16, 2025.
With 24.4 points per game on offense, the Buccaneers rank 11th in the NFL. Defensively, they rank 14th, giving up 22.9 points per game. The Bills are compiling 27.6 points per game on offense (sixth in NFL), and they rank 11th on defense with 21.9 points allowed per game.
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Buccaneers vs Bills: Live streaming info, TV channel & game timeGame day: Sunday, November 16, 2025Game time: 1 p.m. ETLocation: Orchard Park, New YorkStadium: Highmark StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
Watch Buffalo Bills vs. Tampa Bay Buccaneers on Fubo! (Regional restrictions may apply)
Buccaneers vs Bills betting lines
NFL odds courtesy of BetMGM. Odds updated Saturday at 4:29 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Bills (-5.5)Moneyline: Bills (-268), Buccaneers (+216)Total: 46.5 points
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