Oddsmakers give the Buffalo Bills (7-3) the advantage on Thursday, November 20, 2025 against the Houston Texans (5-5). Buffalo is favored by 5.5 points.
Bills vs. Texans game info
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Bills vs. Texans odds & betting linesSpread favorite: Buffalo (-5.5)Moneyline: Buffalo (-257), Houston (+210)Total: 43.5 points
NFL odds courtesy of BetMGM Sportsbook. Odds updated Monday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Bills vs. Texans recent matchupsHouston is 3-1 versus Buffalo in the last four matchups between the two teams.Buffalo scored 92 points in those four matchups, with Houston putting up 65.Bills vs. Texans betting insightsBuffalo is 5-5-0 against the spread so far this season. The Bills have been favored on the moneyline for eight games this season, and they have put together a 5-3 record in those outings. Houston is 4-6-0 against the spread this season. This will be the fourth time this year the Texans are an underdog on the moneyline. They have lost every game.Bills scoring insightsThe Bills are averaging more points at home (32.5) than on the road (24.3).On defense, Buffalo’s average at home, 26.0 points conceded, is higher than its average on the road, 18.3.The Bills average fewer points in division games (23.5) than against the rest of the league (33.0).Buffalo has given up 21.0 points per game in the division, which is lower than its mark against the rest of the league of 24.2.Looking at the Bills’ last three contests, they have posted 28.3 points per game on offense (eighth-ranked) and have surrendered 27.7 points per game on defense (24th-ranked).Texans scoring insightsAt home, the Texans are averaging more points (24.4) than on the road (19.6).Defensively, Houston allows more points at home (16.4 per game) than on the road (16.2), but not by much.Offensively, the Texans average the same number of points in division games as they do against the rest of the league (22.0).Houston has allowed 14.8 points per game in the division, which is lower than its average in non-division games of 17.3.The Texans are 19th in the NFL in points scored for the past three games (22.3 per game) and 11th in points conceded (20.0).Bills injury reportBills: No injuries listedTexans injury reportTexans: No injuries listed
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