Arkansas State vs. Louisiana odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:26 p.m.

Moneyline (ML): Arkansas State -146 (Bet $146 to win $100) | Louisiana +122 (Bet $100 to win $122)Against the spread (ATS): Arkansas State -2.5 (-121) | Louisiana +2.5 (-103)Over/Under (O/U): 53.5 (O: -111 | U: -109)Arkansas State vs. Louisiana betting tips preview

The Arkansas State Red Wolves (5-5) meet a conference opponent when they host the Louisiana Ragin’ Cajuns (4-6) on Thursday, November 20, 2025 at Centennial Bank Stadium in a Sun Belt battle. The game will be broadcast on ESPN, beginning at 7:30 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around Arkansas State vs. Louisiana odds, and make our expert college football picks and predictions.

In their last game, the Red Wolves lost 27-21 to the Southern Miss Golden Eagles. Their last time out, the Ragin’ Cajuns won 42-39 over the Texas State Bobcats. Jaylen Raynor had 331 yards on 37-of-48 passing (77.1%) for the Red Wolves in that matchup against the Golden Eagles, with two touchdowns and four interceptions. He also added 10 carries for 23 yards. Devin Spencer carried the ball 11 times for 47 yards (4.3 yards per carry). He added one reception for seven yards. Corey Rucker led the receiving charge against the Golden Eagles, catching seven passes for 123 yards. D’Wayne Winfield went 17-for-27 with 192 yards, three touchdowns and two interceptions for the Ragin’ Cajuns against the Bobcats. He also rushed 18 times for 49 yards and two touchdowns. Elijah Davis carried the ball 18 times for 87 yards and one touchdown. He caught one pass for eight yards. Shelton Sampson Jr. collected five catches for 80 yards (on eight targets), with two touchdowns.

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Arkansas State vs. Louisiana picks and predictionsPrediction

Arkansas State 30, Louisiana 23

MoneylineMoneyline pick: Arkansas State -146Arkansas State has gone 2-1 in games it was favored on the moneyline (winning 66.7% of those games).The Red Wolves have played as a moneyline favorite of -146 or shorter in only two games this season, and they split 1-1.Louisiana has been an underdog in seven games this season and won three (42.9%) of those contests.The Ragin’ Cajuns have a record of 2-4 when they’re set as an underdog of +122 or more by sportsbooks this season.Against the spreadATS pick: Arkansas State -2.5The Red Wolves have beaten the spread seven times in 10 games.Arkansas State has won once ATS (1-1) as a 2.5-point or higher favorite this year.The Ragin’ Cajuns have covered the spread four times in nine games.Against the spread as 2.5-point underdogs or greater, Louisiana is 4-3.

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