As the NFL heads into Week 12, several teams are dealing with some major injury questions. The 2025 NFL season is nearing its conclusion in November, so teams are facing a crunch time for maintaining healthy bodies.

For NFL fans and fantasy managers, the injury list is critical for understanding who might be out or limited in the upcoming games. Here’s a breakdown of the notable injuries and what you need to know about them heading in.

Bucky Irving, RB, and Chris Godwin, WR, Tampa Bay Buccaneers

On Tuesday, Buccaneers head coach Todd Bowles offered an update on the status of running back Bucky Irving and wide receiver Chris Godwin.

According to Bowles, both players will see more action in practice this week. Irving has been dealing with foot and shoulder injuries, while Godwin has been dealing with a fibula injury.

According to the PFSN NFL RB Impact metrics, Irving has an NFL RB Impact Score of 61.4 and grades out at a D-. According to the PFSN NFL Offense Impact metrics, the Buccaneers have an NFL Offense Impact Score of 73.4 and grade out at a C.

Trey Benson and Emari Demercado, RBs, Arizona Cardinals

Cardinals running back Trey Benson has been sidelined with a knee injury and remains on Injured Reserve at this time. The Cardinals have not announced any updates on his status as of Tuesday.

Benson’s return, though, might be soon, with news coming out on fellow Cardinals running back Emari Demercado. ESPN NFL Insider Adam Schefter reported on Tuesday that Demercado suffered a high ankle sprain against the San Francisco 49ers last Sunday. It looks like Demercado will miss Arizona’s next game against the Jacksonville Jaguars.

Initial tests revealed that Cardinals RB Emari Demercado suffered a high ankle sprain against the 49ers and now is unlikely to play Sunday vs. the Jaguars, per source. pic.twitter.com/HThlzU9mHm

— Adam Schefter (@AdamSchefter) November 18, 2025

According to the PFSN NFL Offense Impact metrics, the Cardinals have an NFL Offense Impact Score of 72.4, grading out to a C-.

Joe Mixon, RB, C.J. Stroud, QB, and Jalen Pitre, S, Houston Texans

There remains no new update on the status of Texans running back Joe Mixon. When Texans head coach DeMeco Ryans met with reporters on Tuesday, he didn’t have any new news on Mixon.

But Texans general manager Nick Caserio, in an appearance on Sports Radio 610 in Houston, offered some thoughts about Mixon potentially returning.

“It’s a very gray situation,” Caserio said. “Joe’s worked at it. There were times where he’s made progress and other times when the progress is kinda stalled. Obviously we’re getting pretty late in the game here, I don’t want to establish any sort of expectations. I don’t think we have anymore clarity at this point.”

As for quarterback C.J. Stroud and safety Jalen Pitre, Ryans said that both players, who are currently in concussion protocol, have been ruled out of Thursday’s game against the Buffalo Bills. With Stroud out, backup quarterback Davis Mills will make his third straight start for the Texans. Stroud, though, did return to the Texans’ practice field on Tuesday.

Additionally, ESPN Texans reporter DJ Bien-Aime reported on Tuesday that Stroud is expected to be available for the team’s Week 13 game on the road against the Indianapolis Colts.

According to the PFSN NFL Offense Impact metrics, the Texans have an NFL Offense Impact Score of 71.0, grading out to a C-.

Brian Thomas Jr., WR, Jacksonville Jaguars

Jaguars wide receiver Brian Thomas Jr. has been working his way back into playing shape after suffering an ankle injury.

On Tuesday, the Jaguars did not have an update available on Thomas’ status. He did not play last Sunday against the Los Angeles Chargers.

According to the PFSN NFL WR Impact metrics, Thomas has an NFL WR Impact Score of 67.9 and grades out to a D+.

Aaron Rodgers, QB, Pittsburgh Steelers

Steelers quarterback Aaron Rodgers left last Sunday’s game with an injured left wrist. On Tuesday, Steelers head coach Mike Tomlin said that Rodgers has a fracture in his left wrist that will not need surgery, according to Schefter. His status for Sunday’s game against the Chicago Bears remains uncertain at this time.

Steelers HC Mike Tomlin told reporters that Aaron Rodgers has a fracture in his wrist that will not require surgery. His status for Sunday’s game against Chicago is uncertain.

— Adam Schefter (@AdamSchefter) November 18, 2025

According to the PFSN NFL QB Impact metrics, Rodgers has an NFL QB Impact Score of 69.0 and grades out to a D+.

Michael Penix Jr., QB, Atlanta Falcons

Falcons quarterback Michael Penix Jr. will be out of action for at least four weeks. Penix suffered a left knee injury in Sunday’s game against the Carolina Panthers, according to the Falcons. Kirk Cousins will now start in Penix’s place.

“We are working through the medical process to determine the severity of the injury,” the Falcons reported on Monday. “He will be placed on the reserve/injured list and miss a minimum of four games.”

According to the PFSN NFL QB Impact metrics, Penix has an NFL QB Impact Score of 69.7 and grades out to a D+.

Jaxson Dart, QB, New York Giants

Giants rookie quarterback Jaxson Dart, who missed last Sunday’s game due to a concussion, remains in concussion protocol as of Monday.

Giants interim head coach Mike Kafka offered an update on Dart’s status when meeting with reporters on Monday.

“I’m just going to see that through, talk with the medical, and when they give us the thumbs up, then we’ll take the next action,” Kafka said.

Lane Johnson, T, Philadelphia Eagles

On Sunday, Eagles tackle Lane Johnson suffered a Lisfranc sprain in his foot, according to Dianna Russini of The Athletic. Russini indicates that Johnson’s injury could sideline him for 4-6 weeks.

Out for the Year

James Conner, RB, Arizona Cardinals (Foot)
Miles Sanders, RB, Dallas Cowboys (Ankle/Knee)
Travis Hunter, WR-CB, Jacksonville Jaguars (Knee)
Malik Nabers, WR, New York Giants (Knee)
Antonio Gibson, RB, New England Patriots (Knee)
Carson Wentz, QB, Minnesota Vikings (Non-throwing shoulder)
Spencer Shrader, K, Indianapolis Colts (Knee)
Patrick Jones II, OLB, Carolina Panthers (Back)
Tyreek Hill, WR, Miami Dolphins (Knee)
Trishton Jackson, WR, Arizona Cardinals (Thumb)
Emory Jones, QB, Atlanta Falcons (Concussion)
Dayton Wade, WR, Baltimore Ravens (Rib)
Jonathon Brooks, RB, Carolina Panthers (Knee)
Deion Hankins, RB, Chicago Bears (Shoulder)
Cade McDonald, WR, Cleveland Browns (Undisclosed)
Kye Robichaux, RB, Detroit Lions (Undisclosed)
Irv Smith, TE, Houston Texans (Ankle)
Brevin Jordan, TE, Houston Texans (Knee)
D.J. Montgomery, WR, Indianapolis Colts (Undisclosed)
Joshua Cephus, WR, Jacksonville Jaguars (Undisclosed)
Keaontay Ingram, RB, Kansas City Chiefs (Undisclosed)
Najee Harris, RB, Los Angeles Chargers (Achilles)
Alexander Mattison, RB, Miami Dolphins (Neck)
Jalin Conyers, TE, Miami Dolphins (Leg)
Rondale Moore, WR, Minnesota Vikings (Knee)
Lan Larison, RB, New England Patriots (Foot)
Deneric Prince, RB, New England Patriots (Undisclosed)
Bub Means, WR, New Orleans Saints (Leg)
Bryce Ford-Wheaton, WR, New York Giants (Achilles)
Johnny Wilson, WR, Philadelphia Eagles (Knee)
Donald Parham Jr, TE, Pittsburgh Steelers (Achilles)
Trent Taylor, WR, San Francisco 49ers (Undisclosed)
Kenny McIntosh, RB, Seattle Seahawks (Knee)
Jaden Smith, WR, Tampa Bay Buccaneers (Undisclosed)
Will Levis, QB, Tennessee Titans (Shoulder)
Austin Ekeler, RB, Washington Commanders (Achilles)
Tyree Jackson, TE, Washington Commanders (Undisclosed)