Check out best bets for when the Buffalo Bills (7-3) and the Houston Texans (5-5) square off at NRG Stadium on Thursday, November 20, 2025.
Watch Buffalo Bills vs. Houston Texans on Fubo! (Regional restrictions may apply)
Best Bills vs. Texans against the spread pickPick ATS: Texans (+6)Buffalo has gone 5-5-0 ATS this season.The Bills have an against-the-spread record of 3-4 in their seven games when favored by 6 points or more so far this season.In 10 games played Houston has recorded four wins against the spread.Best Bills vs. Texans over/under pickPick OU: Over (43.5)The Bills and their opponents have scored more than 43.5 total points six times this season.Texans games this season have had a combined scoring total higher than 43.5 points in three of 10 outings.The teams average 51.2 points per game combined, 7.7 more points than this game’s total.Opponents of these two teams average 39.2 points per game combined, 4.3 fewer than this matchup’s total.Best Bills vs. Texans moneyline betMoneyline pick: Texans +230The Bills have an implied moneyline win probability of 74.0% in this matchup.Buffalo is 5-3 in games they were favored on the moneyline (winning 62.5% of those games).The Bills are 5-2 (winning 71.4% of their games) when they have played as a moneyline favorite of -285 or shorter.This season, Houston has been listed as the underdog in three games and failed to win any of those contests.The Texans have not entered a game this season as a bigger underdog on the moneyline than the +230 odds on them winning this game.How to watch Bills vs. TexansWhen: Thursday, November 20, 2025 at 8:15 p.m. ETWhere: NRG Stadium in Houston, TexasTV info: Amazon Prime VideoLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Amazon Prime!
Watch Buffalo Bills vs. Houston Texans on Fubo! (Regional restrictions may apply)