The New York Giants (2-9) visit the Detroit Lions (6-4) at Ford Field in Detroit for a Week 12 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, November 23, including live updated odds and injury report news.
NameWeek 102025 SeasonJon Hoefling7-884-77-3Blake Schuster11-483-65-3Tyler Dragon6-982-79-3Chris Bumbaca11-478-83-3Lorenzo Reyes6-977-86-3Jordan Mendoza7-864-68-2Richard MorinN/A25-12-1Lions vs. Giants live odds, moneyline, over/under
Opening Lines
Spread: Lions (-8.5)Moneyline: Lions (-410), Giants (+320)Over/Under: 45.5
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Lions vs. Giants picks against the spreadJon Hoefling: Detroit Lions (-10.5)
While the Giants were able to keep it close against Green Bay, they won’t get lucky again without Jaxson Dart. So long as Dan Campbell doesn’t pass up on 25 field goals again, this shouldn’t be much of a struggle for the Lions.
Jordan Mendoza: Detroit Lions (-10.5)
Dan Campbell has to feel irate with how the offense did against the Eagles. Jared Goff and company fix those problems against the Giants.
Lorenzo Reyes: Detroit Lions (-10.5)
It was an ugly showing for the Lions against the Eagles, but New York’s defense doesn’t come close to Philly’s. I don’t see Detroit having consecutive down games, so, with this at home, I’m big on the Lions.
Tyler Dragon: Detroit Lions (-10.5)
Detroit’s offensive line hasn’t played well in recent weeks. The Giants d-line could have some advantages. But I still like the Lions to win this one.
Blake Schuster: Detroit Lions (-10.5)
Detroit has covered as a double digit favorite both times this season. The Lions take care of business.
Christopher Bumbaca: Detroit Lions (-10.5)
Come on back into the winners circle, Dan Campbell. We missed you.
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