DraftKings released the betting lines and odds for every game in the 2025 season. Check out how many times the Cardinals are favored.
The 2025 NFL regular-season schedule has been released and we know when the Arizona Cardinals face all their schedule opponents. They start the season on the road against the New Orleans and close out the year with two road games against the Cincinnati Bengals and Los Angeles Rams.
The Cardinals believe they will be competitive and the feeling is they should make the playoffs in 2025. Now, is that the sentiment around the league?
DraftKings Sportsbook released betting odds and lines for all NFL games.
Let’s have a look at how many games the Cardinals are favored in.
Arizona Cardinals 2025 betting lines for every game
Week 1: New Orleans Saints
The Cardinals are 3.5-point road favorites.
Week 2: Carolina Panthers
The Cardinals are 4.5-point home favorites.
Week 3: San Francisco 49ers
The Cardinals are 3.5-point road underdogs.
Week 4: Seattle Seahawks
In their Week 4 Thursday night game against the Seahawks, the Cardinals are 2.5-point favorites.
Week 5: Tennessee Titans
The Cardinals are 5.5-point home favorites against Tennessee.
Week 6: Indianapolis Colts
The Cardinals are 1.5-point road favorites.
Week 7: Green Bay Packers
The Cardinals are underdogs at home for the first time as the Packers are 1.5-point favorites.
Week 8: Bye
Week 9: Dallas Cowboys
The Cardinals are 1.5-point road underdogs for their Monday night game against the Cowboys.
Week 10: Seattle Seahawks
The Cardinals are 1.5-point road dogs.
Week 11: San Francisco 49ers
They are 1.5-point home underdogs against the Niners.
Week 12: Jacksonville Jaguars
After four consecutive games as the underdog, they are three-point favorites at home against the Jaguars.
Week 13: Tampa Bay Buccaneers
The Cardinals are 3.5-point road underdogs against the Bucs.
Week 14: Los Angeles Rams
Despite being at home, the Cardinals are 1.5-point underdogs.
Week 15: Houston Texans
Arizona is a 2.5-point road dog against Houston.
Week 16: Atlanta Falcons
After three consecutive weeks as the underdogs, the Cardinals are 3.5-point home favorites against Atlanta.
Week 17: Cincinnati Bengals
The Cardinals are back to being road dogs. The Bengals are 3.5-point favorites.
Week 18: Los Angeles Rams
To close out the regular season, the Cardinals are 3.5-point road underdogs.
Takeaways from Arizona Cardinals 2025 betting lines
The Cardinals are favored in only six of their 17 games right now.
They are underdogs in seven of their nine road games. They are favored in four of their eight home games.
They are underdogs in five of their six division games.
As the season progresses, those spreads will change, but for now we can assume the general public does not expect the Cardinals to be better in 2025 than their 8-9 record last year.
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