Patrick Mahomes and the Kansas City Chiefs (5-5) will host Tyler Warren and the Indianapolis Colts (8-2) on Sunday at 1 p.m. ET, in a matchup between two of the biggest stars in the NFL on offense.
The Colts’ defense ranks ninth in the NFL with 20.6 points surrendered per game, but they’ve been bolstered by their offense, which ranks best by putting up 32.1 points per contest. From an offensive standpoint, the Chiefs rank seventh in the NFL with 364.2 yards per game. Meanwhile, they rank seventh in total defense (296.8 yards allowed per contest).
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Colts vs Chiefs: Live streaming info, TV channel & game timeGame day: Sunday, November 23, 2025Game time: 1 p.m. ETLocation: Kansas City, MissouriStadium: GEHA Field at Arrowhead StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
Watch Kansas City Chiefs vs. Indianapolis Colts on Fubo! (Regional restrictions may apply)
Colts vs Chiefs betting lines
NFL odds courtesy of BetMGM. Odds updated Saturday at 8:15 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Chiefs (-3.5)Moneyline: Chiefs (-184), Colts (+153)Total: 49.5 points
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