49ers dominate Panthers: McCaffrey's historic night and key stats from 20-9 win

Published Nov 24, 2025 • 3 hrs ago

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The San Francisco 49ers improved to 8-4 on the season after a 20-9 Week 12 win over the Carolina Panthers at Levi’s Stadium in Santa Clara, California.

Below are several statistics and notes from Monday’s game, which were provided by the 49ers Communications staff.

With The Win…

The San Francisco 49ers have improved to 11-13 all-time against the Carolina Panthers, including a 5-7 record at home.

The 49ers have won three consecutive regular-season games against the Panthers.
San Francisco has improved to 3-0 in primetime games this season [W, 26-23 (OT) at LAR (10/2/25); W, 20-10 vs. Atl. (10/19/25)].
The Niners have won their 54th game on Monday Night Football, tying the Pittsburgh Steelers for the most wins on MNF in NFL history.
Head coach Kyle Shanahan improved to 3-1 against Carolina and 12-6 against the NFC South as head coach of the 49ers.

Big-Time Opening Drive

On the 49ers first offensive possession of the game, the unit registered a 15-play, 72-yd. drive that resulted in a 12-yd. TD pass from QB Brock Purdy to WR Jauan Jennings.
The unit’s 15-play scoring drive marked the first time the 49ers offense has opened the game with a TD drive that was 15-or-more plays since registering an 18-play, 93-yd. TD drive vs. LAR (11/15/21).

49ers Defense

The 49ers defense held the Panthers to converting on just 1 of their 7 third down atts. (14.3%) on the night.
It marks the lowest opponent third down conversion percentage the unit has allowed since they held the Miami Dolphins to converting on 0 of their 7 third down atts. (0.0%) vs. Mia. (12/4/22).

RB Christian McCaffrey

RB Christian McCaffrey registered 24 carries for 89 yds. and 1 TD on the ground to go along with 7 recepts. for 53 yds. through the air. McCaffrey’s rushing TD gives him 7 this season and 59 in his career.
With 7 recepts. on the night, McCaffrey has tallied 81 recepts. this season. His 81 recepts. mark the 5th time in his career that he has registered 75-or-more recepts. in a season, making him the 4th RB in NFL history to record at least 75 recepts. in 5 career seasons, joining former NFL RB Larry Centers, HOF RB Marshall Faulk and New Orleans Saints RB Alvin Kamara.
On the opening drive of the game, McCaffrey registered 6 carries for 28 yds. and 3 recepts. for 12 yds. His 9 total touches tied his career high for the most touches on the opening drive of a game [9 touches vs. GB (12/17/17) as a member of the Carolina Panthers].
With 142 yds. from scrimmage, McCaffrey registered his 10th game this season with 100-or-more yds. from scrimmage, which is the most by any player in the NFL. He also registered his 67th career game with 100-or-more yds. from scrimmage and his 30th such game as a member of the 49ers.
McCaffrey’s 67 games with 100-or-more yds. from scrimmage are the most among active NFL RBs.

MOST GAMES WITH 100-OR-MORE YDS. FROM SCRIMMAGE, ACTIVE NFL RBs

Rank
Player
Games

1.
RB Christian McCaffrey, Car./SF
67

2.
RB Derrick Henry, Ten./Bal.
63

3.
RB Alvin Kamara, NO
59

4.
RB Saquon Barkley, NYG/Phi.
50

5.
RB Josh Jacobs, Oak./LV/GB
42

McCaffrey’s 30 games with 100-or-more yds. from scrimmage surpass former RB Garrison Hearst for the 4th-most such games in franchise history.

MOST GAMES WITH 100-OR-MORE YDS. FROM SCRIMMAGE, FRANCHISE HISTORY

Rank
Player
Games

1.
WR Jerry Rice
70

2.
RB Frank Gore
66

3.
RB Roger Craig
50

4.
RB Christian McCaffrey
30

5.
RB Garrison Hearst
29

With 89 rushing yds. and 53 rec. yds., McCaffrey recorded his 38th career game with 50-or-more rushing yds. and 50-or-more rec. yds., which is the 2nd-most such games in NFL history (RB Marshall Faulk, Ind./StL – 41 games).

MOST GAMES WITH 50-OR-MORE RUSHING YDS. AND 50-OR-MORE REC. YDS., NFL HISTORY

Rank
Player
Games

1.
RB Marshall Faulk, Ind./StL
41

2.
RB Christian McCaffrey, Car./SF
38

3.
RB Alvin Kamara, NO
24

4t.
RB Tiki Barber, NYG
23

RB LaDanian Tomlinson, SD/NYJ
23

Of those 38 games, McCaffrey has recorded 14 as a member of the 49ers. His 14 games with 50-or-more rushing yds. and 50-or-more rec. yds. are tied for the 2nd-most in franchise history.

MOST GAMES WITH 50-OR-MORE RUSH YDS. AND 50-OR-MORE REC. YDS., FRANCHISE HISTORY

Rank
Player
Games

1.
RB Roger Craig
17

2t.
RB Christian McCaffrey
14

RB Frank Gore
14

4.
RB Ricky Watters
8

5.
RB Charlie Garner
7

McCaffrey’s 53 rec yds. mark his 50th career game with 50-or-more rec. yds., which is tied for the 2nd-most games with at least 50 rec. yds. by a RB in the Super Bowl Era.

MOST GAMES WITH 50-OR-MORE REC. YDS. BY A RB, SUPER BOWL ERA

Rank
Player
Games

1.
RB Larry Centers, Pho./Arz./Was./Buf./NE
55

2t.
RB Christian McCaffrey, Car./SF
50

RB Marshall Faulk, Ind./StL
50

4.
RB Ronnie Harmon, Buf./SD/Hou.
47

5.
RB Keith Byars, Phi./Mia./NE/NYJ
46

WR Jauan Jennings

WR Jauan Jennings tallied 5 recepts. for 41 yds. and 1 TD on the day. His TD recept. marked his 4th of the season and the 17th of his career.

S Ji’Ayir Brown

S Ji’Ayir Brown notched5 tackles and 2 INTs of Panthers QB Bryce Young on the night, marking his first INTs of the season and giving him 5 in his career.
Brown’s INTs of Young marked his first since he registered 1 INT vs. Dal. (10/27/24).
With 2 INTs on the night, Brown became the first 49ers player to register 2-or-more INTs in a single game since former CB Charvarius Ward in 2023 [2 INTs at Arz. (12/17/23)].

DL Clelin Ferrell

DL Clelin Ferrell notched 1 tackle and 1 sack of Young on the night. His sack gives him 2.0 on the season and 19.0 in his career.

LB Nick Martin

LB Nick Martin tallied 2 tackles on special teams and registered 1 special teams FF, marking the first special teams FF of his career.

K Matt Gay

K Matt Gay converted on each of his FGAs (47 & 29) and both of his PATs in his debut with the team.

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49ers dominate Panthers: McCaffrey’s historic night and key stats from 20-9 win

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