The Green Bay Packers (7-3-1) and Detroit Lions (7-4) meet on Thanksgiving Day on Thursday for a Week 13 matchup. Kickoff from Ford Field in Detroit is scheduled for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Packers vs. Lions odds and make our expert NFL picks and predictions for the best bets.

The Packers lead the all-time series 107-78-7. The home team won both meetings in 2024, with the Packers going 2-0 against the spread (ATS). Their last meeting on Thanksgiving Day was Nov. 23, 2023, with Green Bay winning 29-22 in Detroit as an 8.5-point underdog as the Over (47) cashed.

Green Bay blasted the Minnesota Vikings 23-6 last week as a 6.5-point favorite as the Under (41.5) cashed, halting a 3-game non-cover skid. The Packers are just 2-7 ATS in the past 9 games, too, while the Under is 3-1 in the past 4 outings.

Packers RB Josh Jacobs (knee) did not play in Week 12, so RB Emanuel Wilson filled in. He had 28 carries for 107 yards and 2 TDs. QB Jordan Love left the game briefly, but returned to finish. He had just 139 yards and 15 rushing yards. Jacobs was a limited participant in practice all week, but he was removed from the injury report Wednesday afternoon, so he’ll play. The same is true for Love, who had a left shoulder injury, but he practiced in full Wednesday.

The Lions avoided embarrassment, holding off the New York Giants 34-27 in overtime as a 14-point favorite last week as the Over (50.5) cashed. RB Jahmyr Gibbs went off for 219 rushing yards and 2 TDs, while posting 11 receptions for 45 yards and a score. WR Amon-Ra St. Brown posted 9 grabs for 149 yards and a score. Still, the Lions are just 3-3 SU in the past 6 games, while going 1-3 ATS in the past 4 outings. The Over is 3-1 in the 4-game span, too.

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Packers at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:29 p.m. ET.

Moneyline (ML): Packers +135 (bet $135 to win $100) | Lions -160 (bet $160 to win $100)Against the spread: Packers +3 (-115) | Lions -3 (-105)Over/Under (O/U): 48.5 (O: -110 | U: -110)

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Packers at Lions key injuries

Packers

DL Karl Brooks (ankle) outWR Matthew Golden (wrist) questionableCB Nate Hobbs (knee) questionableCB Keisean Nixon (neck) questionableWR Jayden Reed (foot, shoulder) outDL Lukas Van Ness (foot) outLB Quay Walker (neck) questionableWR Savion Williams (foot) out

Lions

CB Terrion Arnold (concussion) questionableDE Marcus Davenport (shoulder) questionableOT Taylor Decker (shoulder) questionableOG Mile Frazier (knee) questionableC Graham Glasgow (knee) outS Kerby Joseph (knee) outDE Joshua Paschal (back) outOG Tate Ratledge (knee) questionableWR Kalif Raymond (ankle) outOT Penei Sewell (ankle) questionableWR Isaac TeSlaa (hand) questionableRB Sione Vaki (ankle, thumb) questionableTE Brock Wright (neck) outPackers at Lions picks and predictionsPrediction

Packers 27, Lions 24

The PACKERS (+135) are worth a look as slight underdogs.

Green Bay won at Ford Field in its most recent trip on Thanksgiving, and it’s a good bet to do so again. Wednesday’s afternoon practice presented the Packers with good news, as Jacobs was able to practice on a limited basis again, and he was removed from the team’s injury report. Love, dealing with a left shoulder issue, also made it through practice, and he is good to go. That’s huge.

On the flip side, Detroit will be without Wright, who is already replacing TE Sam LaPorta (back). The depth for the Lions has taken a hit, and with Decker and Sewell questionable, and Glasgow out, the offensive line could struggle. Things are so bad on the O-line that C Frank Ragnow agreed Wednesday to come out of retirement, although he isn’t likely to play Thursday. He was moved from the reserve/retired list to the exempt/commissioner permission list Wednesday.

Play the PACKERS +3 (-115) catching the field goal, in case you’re feeling a close game, but you’d like a little wiggle room.

The Lions struggled last week, and they’re just 2-4 ATS in the past 6 games. The Lions have allowed 22 or more points in 3 of the past 4 games, and 5 of the past 7 games, too.

OVER 48.5 (-110) is a decent play in the first game of Thanksgiving.

The Over has cashed in 3 of the past 4 games for the Lions, as they’ve scored 24 or more points in 4 of the past 5 games, and 8 of the past 10 games. The Under is 3-1 in the past 4 games for the Packers, though, so be careful.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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