Dallas Cowboys star receiver George Pickens missed some practice time early in the week with a knee injury, but he’s not listed on the team’s final injury report for Thursday’s matchup with the Kansas City Chiefs.

Cowboys WR George Pickens has no injury designation for Thursday’s game against the Chiefs and is good to go.

— Adam Schefter (@AdamSchefter) November 26, 2025

Pickens has been a revelation for the Cowboys this season, racking up over 1,000 receiving yards in 11 games. He’s been a great 1B to CeeDee Lamb’s 1A on offense, and he could be in line for a big day with the total in this game set at 52.5.

The Cowboys are underdogs in the latest betting odds for this matchup, but they have a strong record this season when both Pickens and Lamb play, and they’ve won two games in a row since the trade deadline.

Here’s a look at my favorite prop bet for Pickens in this Thanksgiving matchup.

Odds via DraftKings Sportsbook.

George Pickens OVER 5.5 Receptions (+110)

The 2025 season has been a fun one for Pickens, as he’s already up to 1,054 receiving yards and eight scores in 11 games.

Pickens has become the perfect complement to Lamb in the Dallas offense, and he’s actually looked like the No. 1 option at times in recent weeks. The former second-round pick has at least nine targets in each of his last four games, coming down with seven, six, nine and nine receptions in those contests.

In fact, he has six games this season with at least six catches. So, getting him at plus money in this market in a potential shootout seems like a pretty good deal.

The Cowboys are third in the NFL in passing yards, so I’d expect Pickens to get plenty of looks on Thanksgiving as Dallas aims to pull off another upset.

Odds refresh periodically and are subject to change.

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