Houston (6-5) rides a three-game winning streak into a matchup with Indianapolis (8-3) on Sunday, November 30, 2025 at Lucas Oil Stadium. The Colts are listed as favorites in this one, with the spread sitting at 3.5 points. The over/under is 44.5 in the outing.
In their most recent action, the Colts lost versus the Kansas City Chiefs, 23-20.
Colts QB Daniel Jones was 19-for-31 for 181 yards, with two TDs and no INTs, versus the Chiefs.
Against the Buffalo Bills in their last contest, the Texans won 23-19.
Colts vs Texans betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 1:07 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Indianapolis (-3.5)Moneyline: Indianapolis (-188), Houston (+156)Total: 44.5 pointsColts betting insightsAt home this season, Indianapolis is 6-0 overall and 4-2 against the spread.The Colts have put together a record of 7-4-0 against the spread this season.Indianapolis has two wins ATS (2-2) as 3.5-point favorites or greater at home.In games they have played as 3.5-point favorites or more, the Colts have an ATS record of 3-2.This year, Indianapolis has gone over the total in four of six home games.Colts games have gone over the total six times this season.Colts leadersJones: 2,840 PASS YDS / 258.2 YPG / 69.1% / 17 TD / 7 INT / 43 CAR / 159 RUSH YDS / 5 TDJonathan Taylor: 205 CAR / 1,197 YDS / 108.8 YPG / 15 TD / 32 REC / 268 YDS / 24.4 YPG / 2 TDTyler Warren: 55 REC / 662 YDS / 60.2 YPG / 3 TDAlec Pierce: 29 REC / 611 YDS / 67.9 YPG / 1 TDMichael Pittman Jr.: 59 REC / 607 YDS / 55.2 YPG / 7 TDColts vs Texans game infoDate: Sunday, November 30, 2025Time: 1 p.m. ETCity: Indianapolis, IndianaVenue: Lucas Oil StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)
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