An exciting offensive matchup is set for Thursday Night Football in Week 14, as the Dallas Cowboys and Dak Prescott hit the road to play the Detroit Lions.

Both of these teams played on Thanksgiving Day, but they had very different results. 

Detroit struggled against the Green Bay Packers, scoring just 21 points in a 10-point loss to fall further out of the playoff race in the NFC. Dallas, on the other hand, picked up an upset win over the Kansas City Chiefs to move to 6-5-1 in the 2025 season.

Dallas is also on the outside of the playoff picture, but wins over Philadelphia and Kansas City have suddenly put it back in the mix to make the postseason in 2025.

Dak Prescott is now No. 3 in the odds to win the MVP, and he’s led an explosive passing attack with CeeDee Lamb, George Pickens and Jake Ferguson. 

Could the Cowboys put up some big numbers against a struggling – and banged up – Detroit defense? 

Here’s a breakdown of some of my favorite prop bets for this primetime matchup in Week 14. 

Odds via DraftKings Sportsbook.

George Pickens OVER 5.5 Receptions (-132)

Pickens has been on fire as of late, catching six or more passes in each of his last five games, including a six-catch game (for 88 yards) on Thanksgiving against the Chiefs.

Prescott targeted Pickens 13 times in that game, and the former second-round pick has at least nine targets in each of his last five games. In the 2025 season, Pickens has been targeted nine or more times nine of Dallas’ 12 games, giving him a great floor when it comes to this prop.

Overall, the star receiver has 105 targets, 73 receptions, 1,142 receiving yards and eight scores. He should make some noise against a Detroit defense that is 16th in the NFL in EPA/Pass and allowed four scores through the air to the Green Bay Packers on Thanksgiving. 

Jared Goff OVER 249.5 Passing Yards (-113)

Lions quarterback Jared Goff has thrown for 250 or more passing yards in each of his last five games, throwing for 256 yards on just 26 passes on Thanksgiving. 

Goff has only cleared this prop in seven of his 12 games overall, but this is a great matchup against a Dallas defense that is 29th in the league in EPA/Pass and has allowed the third-most passing yards in the NFL. 

The Cowboys have given up over 250 passing yards per game, and they allowed Patrick Mahomes to throw for 261 yards on Thanksgiving. I’m buying Goff to have a big game at home on Thursday. 

Javonte Williams UNDER 68.5 Rushing Yards (-112)

Javonte Williams has monopolized touches in the Dallas backfield, playing 75.5 percent of the snaps this season and carrying the ball 17 times for 59 yards on Thanksgiving. 

He’s cleared 68.5 rushing yards in eight of his 12 games this season, but this is a tough matchup against a Detroit defense that is No. 3 in the NFL in EPA/Rush.

The Lions are allowing just 3.9 yards per carry this season (fifth in the NFL), and they only allowed 969 rushing yards to opposing running backs (80.75 per game) this season. 

Even though Williams should see 15 or more touches in this game, I think this number is a little high against a defense that is much easier to beat through the air. Dallas should lean on Pickens and Lamb to lead the offense on Thursday.

Odds refresh periodically and are subject to change.

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