They already knew they were going to be missing Brandon Aiyuk for much of the season, and from that point have also sustained injuries to Nick Bosa, George Kittle, Fred Warner, Ben Bartch, Brock Purdy, and Ricky Pearsall, among others. As a result, they’ve lost the most potential productivity to injury of any team in the NFL.
The value we’re measuring here is each injured player’s Total Points per game over his previous 17 games, multiplied by the number of games missed due to injury. This only counts injuries sustained since August 1.