Jacksonville (8-4) takes a three-game winning streak into a matchup with Indianapolis on Sunday, December 7, 2025 at EverBank Stadium. The spread foretells a close game, with the Colts favored by 1.5 points. The over/under is 46.5 in the contest.
Against the Tennessee Titans in their last contest, the Jaguars won 25-3.
Against the Titans, Trevor Lawrence completed 16 of 27 attempts for 229 yards, with two touchdowns and no interceptions, for the Jags.
In their most recent action, the Colts lost against the Houston Texans, 20-16.
Jaguars vs Colts betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 5:39 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Indianapolis (-1.5)Moneyline: Indianapolis (-129), Jacksonville (+109)Total: 46.5 pointsJaguars betting insightsJacksonville is 4-2 against the spread, and 4-2 overall, at home.The Jaguars are 7-5-0 against the spread this season.At home, Jacksonville has two wins ATS (2-2) as 1.5-point underdogs or greater.In games they have played as 1.5-point underdogs or more, the Jaguars have an ATS record of 3-3.Jacksonville has gone over the total once in six home games this year.Jaguars games have finished with a final combined score above the over/under six times this season.Jaguars leadersLawrence: 2,636 PASS YDS / 219.7 YPG / 59.7% / 16 TD / 11 INT / 57 CAR / 235 RUSH YDS / 5 TDTravis Etienne: 181 CAR / 843 YDS / 70.3 YPG / 5 TD / 25 REC / 173 YDS / 14.4 YPG / 2 TDBhayshul Tuten: 75 CAR / 272 YDS / 22.7 YPG / 4 TD / 9 REC / 63 YDS / 5.3 YPG / 1 TDJakobi Meyers: 51 REC / 597 YDS / 54.3 YPG / 2 TDBrian Thomas: 32 REC / 448 YDS / 49.8 YPG / 1 TDParker Washington: 36 REC / 447 YDS / 37.3 YPG / 3 TDJaguars vs Colts game infoDate: Sunday, December 7, 2025Time: 1 p.m. ETCity: Jacksonville, FloridaVenue: EverBank StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)
Watch Indianapolis Colts vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)