Jacksonville (8-4) brings a three-game winning streak into a matchup with Indianapolis on Sunday, December 7, 2025 at EverBank Stadium. The spread foreshadows a close game, with the Colts favored by 1.5 points. The over/under in the outing is set at 46.5 points.
The Colts lost versus the Houston Texans in their most recent game, 20-16.
In that game against the Texans, Colts quarterback Daniel Jones completed 14 of 27 passes for 201 yards, with two touchdowns and no interceptions.
In their most recent contest, the Jaguars won against the Tennessee Titans, 25-3.
Colts vs Jaguars betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 9:07 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Indianapolis (-1.5)Moneyline: Indianapolis (-129), Jacksonville (+109)Total: 46.5 pointsColts betting insightsIndianapolis is 3-2 against the spread, and 2-3 overall, away from home.The Colts have covered the spread seven times over 12 games with a set spread.Indianapolis has one win ATS (1-1) away from home as 1.5-point favorites or more.In games this season when favored by 1.5 points or more, the Colts have gone 3-4 against the spread.Indianapolis has hit the over twice in five away games this year.Colts games have finished with a final combined score above the over/under six times this season.Colts leadersJones: 3,041 PASS YDS / 253.4 YPG / 67.9% / 19 TD / 7 INT / 44 CAR / 160 RUSH YDS / 5 TDJonathan Taylor: 226 CAR / 1,282 YDS / 106.8 YPG / 15 TD / 35 REC / 304 YDS / 25.3 YPG / 2 TDAlec Pierce: 33 REC / 689 YDS / 68.9 YPG / 2 TDTyler Warren: 58 REC / 684 YDS / 57.0 YPG / 4 TDMichael Pittman Jr.: 60 REC / 620 YDS / 51.7 YPG / 7 TDColts vs Jaguars game infoDate: Sunday, December 7, 2025Time: 1 p.m. ETCity: Jacksonville, FloridaVenue: EverBank StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)
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