Puka Nacua and the Los Angeles Rams (9-3) will visit Trey McBride and the Arizona Cardinals (3-9) on Sunday at 4:25 p.m. ET, in a matchup between a pair of excellent pass-catchers.
The Rams own the sixth-ranked offense this season (27.8 points per game), and they’ve been more effective on defense, ranking second-best with only 17.5 points allowed per game. In terms of total yards, the Cardinals rank 16th in the NFL (337.3 total yards per game) and 19th defensively (332.2 total yards allowed per game).
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Rams vs Cardinals: live streaming info, TV channel & game timeGame day: Sunday, December 7, 2025Game time: 4:25 p.m. ETLocation: Glendale, ArizonaStadium: State Farm StadiumTV channel: FOXLive stream: Watch on Fubo! (Regional restrictions may apply)
Watch Los Angeles Rams vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)
Rams vs Cardinals betting lines
NFL odds courtesy of BetMGM. Odds updated Sunday at 12:24 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Rams (-9.5)Moneyline: Rams (-529), Cardinals (+394)Total: 47.5 points
Watch Los Angeles Rams vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)