The Arizona Cardinals (3-9) take a four-game losing streak into their contest with the Arizona Cardinals on Sunday, December 7, 2025 at State Farm Stadium. The Rams are significant favorites in this one, with the spread sitting at 9.5 points. An over/under of 47.5 points has been set for the outing.
The Rams lost to the Carolina Panthers, 31-28, in their most recent contest.
Against the Panthers, Matthew Stafford completed 18 of 28 attempts for 243 yards, with two touchdowns and two interceptions, for the Rams.
In their most recent contest, the Cardinals lost against the Tampa Bay Buccaneers, 20-17.
Rams vs Cardinals betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 12:35 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Los Angeles (-9.5)Moneyline: Los Angeles (-529), Arizona (+394)Total: 47.5 pointsRams betting insightsLos Angeles is 4-2 overall, and 4-2 against the spread, away from home.The Rams have covered the spread in a matchup eight times this season (8-4-0).Los Angeles is winless ATS (0-1) as 9.5-point favorites or more on the road.In games they have played as 9.5-point favorites or more, the Rams have an ATS record of 1-1.Los Angeles has gone over the total in four of six away games this season.Rams games have gone over the total five times this season.Rams leadersStafford: 3,073 PASS YDS / 256.1 YPG / 66.3% / 32 TD / 4 INTKyren Williams: 183 CAR / 868 YDS / 72.3 YPG / 7 TD / 24 REC / 184 YDS / 15.3 YPG / 3 TDBlake Corum: 89 CAR / 422 YDS / 35.2 YPG / 2 TDPuka Nacua: 86 REC / 1,019 YDS / 92.6 YPG / 4 TDDavante Adams: 52 REC / 689 YDS / 57.4 YPG / 14 TDColby Parkinson: 23 REC / 191 YDS / 21.2 YPG / 3 TDRams vs Cardinals game infoDate: Sunday, December 7, 2025Time: 4:25 p.m. ETCity: Glendale, ArizonaVenue: State Farm StadiumTV channel: FOXLive stream: Watch on Fubo (Regional restrictions may apply)
Watch Los Angeles Rams vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)