If Patrick Mahomes and the Chiefs (6-7) have a pulse, its faint. Winning their remaining games looks like a must if they are to have a chance of qualifying for the postseason. That gauntlet begins Sunday at Arrowhead against the Chargers (9-4).

Los Angeles defeated the Eagles Monday Night and as a result, climbed over Josh Allen and the Bills into the No. 5 seed. The Chiefs’ loss to C.J. Stroud and the Texans was a fatal blow to their hopes for a tenth consecutive AFC West title. They remain alive for a playoff berth as a Wild Card, but they need plenty of help as alluded to earlier.

These two teams opened the season in Sao Paolo, Brazil. Justin Herbert and the Chargers set the tone for their season with a 27-21 win. The star signal-caller threw for 318 yards and three touchdowns to lead Los Angeles to victory.

Lets dive into the matchup and see what the numbers tell us.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Chargers vs. Chiefs live SundayDate: Sunday, December 14, 2025Time: 1:00PM ESTSite: GEHA Field at Arrowhead StadiumCity: Kansas City, MONetwork/Streaming: CBS

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Game odds for the Chargers at the Chiefs

The latest odds as of Tuesday courtesy of DraftKings:

Moneyline: Los Angeles Chargers (+170), Kansas City Chiefs (-205)Spread: Chiefs -4.5Total: 41.5 points

This game opened at Chiefs -4.0 with the Game Total set at 42.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Los Angeles at Kansas CityChargers Starting QB: Justin Herbert
Last Game: 12/8 vs. Philadelphia – 12-26, 139yds, 1TD, 1INT, Sacked 7 times, 10 carries for 66yds rushing
Season: 13GP, 277-422, 2981yds, 22TDs, 11INTs, Sacked 45 times, 67 carries for 419ydsChiefs Starting QB: Patrick Mahomes
Last Game: 12/7 vs. Houston – 14-33, 160yds, 0TDs, 3INTs, Sacked 2 times, 7 carries for 59yds rushing
Season: 13GP, 299-477, 3398yds, 22TDs, 10INTs, Sacked 29 times, 62 carries for 407yds rushingChargers at Chiefs team stats, betting trendsThe Chiefs have won 4 straight AFC West games at ArrowheadThe Chargers have covered the Spread in 8 straight games against AFC West teamsThe UNDER is 4-1 in the Chiefs’ last 5 games against AFC West teamsThe UNDER is 9-4 this season in Chiefs’ gamesThe OVER has cashed 6 times in Chargers’ games this seasonKansas City is 5-7-1 ATS overall this seasonLos Angeles is 6-6-1 ATS overall this seasonChargers Player InjuriesWR Derius Davis (ankle) is listed as questionable for Sunday’s gameRT Trey Pipkins III (ankle) is listed as questionable for Sunday’s gameS Elijah Molden (hamstring) is listed as questionable for Sunday’s gameTE Tucker Fisk (ankle) has been placed on IR and has been ruled OUT for Sunday’s game
Chiefs Player InjuriesLT Wanya Morris (knee) has been ruled OUT of Sunday’s gameCB Trent McDuffie (knee) is listed as questionable for Sunday’s gameRG Trey Smith (ankle) is listed as questionable for Sunday’s gameRT Jawaan Taylor (triceps) is listed as questionable for Sunday’s gameWR Nikko Remigio (shoulder) is listed as questionable for Sunday’s gameRotoworld Best Bets

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Chargers and the ChiefsMoneyline: Rotoworld Bet is staying away from a play on the Moneyline.Spread: Rotoworld Bet is leaning towards a play ATS on the Kansas City Chiefs at -4.5.Total: Rotoworld Bet is recommending a play on the under on the Game Total of 41.5.

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