The Indianapolis Colts (8-5) visit the Seattle Seahawks (10-3) at Lumen Field in Seattle for a Week 15 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, December 14, including live updated odds and injury report news.

NameWeek 142025 SeasonBlake Schuster9-5108-82-5Jon Hoefling9-5104-99-5Tyler Dragon5-8100-102-5Chris BumbacaN/A83-91-4Lorenzo Reyes8-597-105-5Jordan Mendoza3-1179-95-4Richard Morin5-937-29-2Seahawks vs. Colts live odds, moneyline, over/under

Opening Lines

Spread: Seahawks (-3.5)Moneyline: Seahawks (-185), Colts (+154)Over/Under: 44.5

Get the edge with our exclusive NFL betting picks

Seahawks vs. Colts picks against the spreadBlake Schuster: Seattle Seahawks (-13.5)

I’m not sure who is going to start at quarterback for Indianapolis. I’m not sure it matters considering the Seahawks have arguably the best defense in football.

Jon Hoefling: Seattle Seahawks (-13.5)

Remember when the 49ers had no quarterback in the NFC Championship Game a few years ago? How did that turn out? We’ll probably see something similar here.

Tyler Dragon: Seattle Seahawks (-13.5)

Philip Rivers could play against the Seahawks defense at 44 years old. No thank you.

Jordan Mendoza: Indianapolis Colts (+13.5)

It’s wild seeing how much the Colts have fallen, and it won’t get easier having to play in Seattle. The Colts are able to at least keep this game respectable and limit the Seahawk offense.

Christopher Bumbaca: Seattle Seahawks (-13.5)

Riley Leonard against that Seattle defense? No chance. Philip Rivers against the Seattle defense? Perhaps. But still taking the Seahawks.

Lorenzo Reyes: Seattle Seahawks (-13.5)

Given Indy’s mess at quarterback, hard to see the Colts keeping this close, especially against a stellar Seahawks defense.

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