The Arizona Cardinals (3-10) visit the Houston Texans (8-5) at NRG Stadium in Houston for a Week 15 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, December 14, including live updated odds and injury report news.
NameWeek 142025 SeasonBlake Schuster9-5108-82-5Jon Hoefling9-5104-99-5Tyler Dragon5-8100-102-5Chris BumbacaN/A83-91-4Lorenzo Reyes8-597-105-5Jordan Mendoza3-1179-95-4Richard Morin5-937-29-2Texans vs. Cardinals live odds, moneyline, over/under
Opening Lines
Spread: Texans (-2.5)Moneyline: Texans (-142), Cardinals (+120)Over/Under: 45.5
Get the edge with our exclusive NFL betting picks
Texans vs. Cardinals picks against the spreadBlake Schuster: Houston Texans (-9.5)
The Arizona Cardinals are bad, yes, but more importantly, have you seen that Texans defense lately? I’m not sure the Cardinals can even score 10 points against them.
Jon Hoefling: Houston Texans (-9.5)
The Houston Texans are playing some of their best football right now. The Arizona Cardinals are playing some of their worst. And Arizona has lost by at least 10 points in three of their last five games.
Tyler Dragon: Houston Texans (-9.5)
Will Anderson Jr., Danielle Hunter, Derek Stingley Jr. and the Texans defense are going to give Arizona fits.
Jordan Mendoza: Houston Texans (-9.5)
It doesn’t matter who it’s been, the Texans defense has stopped everybody, not allowing 20 points in the past four games. Arizona is struggling bad and the Texans feast on the opportunity with a comfortable win.
Christopher Bumbaca: Arizona Cardinals (+9.5)
That Texans’ defense remains nasty but that offense still has some serious question marks. Think the Cardinals, coming off a shellacking from the Rams, play with some pride.
Lorenzo Reyes: Houston Texans (-9.5)
Houston’s defense has shown that it can clamp down on even some of the best offenses in the NFL. It is double digits, but this is actually a manageable spread, assuming the Texans can get something out of their ground game.
Texans vs. Cardinals updated injury reportNFL Week 15 picks, predictions, oddsSuper Bowl 60 updated odds