The Los Angeles Rams (10-3) are less than a touchdown favorite (-6) on Sunday, December 14, 2025 against the Detroit Lions (8-5).

Rams vs. Lions game infoGame day: Sunday, December 14, 2025Game time: 4:25 p.m. ETTV channel: FOXLocation: Inglewood, CaliforniaStadium: SoFi StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)

Watch Los Angeles Rams vs. Detroit Lions on Fubo! (Regional restrictions may apply)

Rams vs. Lions odds & betting linesSpread favorite: Los Angeles (-6)Moneyline: Los Angeles (-258), Detroit (+210)Total: 55 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Rams vs. Lions recent matchupsDetroit and Los Angeles have split their last four matchups (2-2).Los Angeles outscored Detroit 101-85 in those four head-to-head matchups.Rams vs. Lions betting insightsLos Angeles, through 13 games with a spread so far this season, has gone 9-4-0 against the spread. The Rams have been listed as moneyline favorites 12 times this season, and they have put together a 10-2 record in those matchups. Detroit, through 13 games with a set spread so far this season, is 7-6-0 against the spread. The Lions’ record is 1-3 when playing as an underdog this year.Rams scoring insightsThe Rams score 25.5 points per game at home, which is lower than their 32.3 average away from home.Defensively, Los Angeles’ average at home, 15.2 points conceded, is better than its average on the road, 19.4.The Rams average more points in division games (32.8) than outside the division (27.6).Los Angeles is giving up 22.0 points per game in divisional matchups, which is higher than its 15.4 average outside the division.On the offensive side of the ball, the Rams have been making things happen over the last three contests, compiling 35.7 points per game (best). They rank ninth over the last three games on defense (18.3 points per game allowed).Lions scoring insightsAt home, the Lions are averaging more points (33.7) than away (26.3).Defensively, Detroit is allowing 22.1 points per game at home, less than its 24.8 average away from home.Offensively, the Lions are putting up 28.3 points per game in divisional matchups, which is lower than their 31.2 average versus the rest of the league.Detroit averages more points conceded in division games (26.5) than against the rest of the league (22.0).The Lions are second-best in the league in points scored for the past three games (34.0 per game) and fourth-worst in points conceded (29.3).Rams injury reportRams:
Davante Adams: Did Not Participate In Practice (Hamstring),
Byron Young: Limited Participation in Practice (Knee),
Darious Williams: Full Participation in Practice (Tibia)Lions injury reportLions:
Shane Zylstra: Limited Participation in Practice (Knee),
Sione Vaki: Limited Participation in Practice (Thumb),
Kalif Raymond: Limited Participation in Practice (Ankle),
Christian Mahogany: Limited Participation in Practice (Fibula),
Kerby Joseph: Did Not Participate In Practice (Knee),
Thomas Harper: Limited Participation in Practice (Concussion),
Kayode Awosika: Limited Participation in Practice (Foot),
Taylor Decker: Did Not Participate In Practice (Shoulder),
Brian Branch: Did Not Participate In Practice (Achilles),
Alex Anzalone: Full Participation in Practice (Illness)

Watch Los Angeles Rams vs. Detroit Lions on Fubo! (Regional restrictions may apply)