Our computer model predicts the Houston Texans will defeat the Arizona Cardinals on Sunday, Dec. 14 at 1 p.m. ET. For a complete projection on the matchup at NRG Stadium, which includes our prediction on the spread, over/under, and final score, keep scrolling.

Don’t miss a touchdown this NFL season. Catch every score with NFL RedZone on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Sign up today and watch seven hours of football from every NFL game every Sunday.

Texans vs. Cardinals Game Info and TV Channel

When: Sunday, December 14, 2025 at 1 p.m. ET
Where: NRG Stadium in Houston, Texas
TV: FOX
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Catch every NFL touchdown with NFL RedZone on Fubo.

Listen to the game on SportsRadio 610

Texans vs. Cardinals Odds and Betting Info

Spread favorite: Texans (-9.5)
Moneyline: Texans (-524), Cardinals (+394)
Total: 42.5 points
Texans vs. Cardinals Prediction

Pick ATS: Texans (-9.5)

Pick OU: Over (42.5)

Prediction:

Texans 31 – Cardinals 12

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

See how these predictions pan out and sign up for NFL RedZone on Fubo to catch every score on Sundays this fall.

Texans vs. Cardinals Betting Insights

The Texans have compiled a 7-6-0 ATS record so far this year.
The Cardinals have won six games against the spread this year, failing to cover seven times.
Arizona has covered the spread once this season (1-1 ATS) when playing as at least 9.5-point underdogs.
The Texans and their opponent have combined to hit the over three out of 13 times this season.
The Cardinals and their opponent have combined to hit the over eight out of 13 times this season.

Looking for NFL tickets? Head to StubHub today and see your team live.