Division rivals Carolina (7-6) and New Orleans (3-10) will meet in a matchup of NFC South teams on Sunday, December 14, 2025 at Caesars Superdome. The betting information foretells a close game, with the Panthers favored by 2.5 points. The over/under is 40.5 in the outing.
Last time out, the Saints defeated the Tampa Bay Buccaneers, with 24-20 being the final score.
Saints quarterback Tyler Shough was 13-for-20 for 144 yards, with no TDs and one INT, against the Buccaneers.
The Panthers won against the Los Angeles Rams in their most recent game, 31-28.
Saints vs Panthers betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 4:31 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Carolina (-2.5)Moneyline: Carolina (-154), New Orleans (+129)Total: 40.5 pointsSaints betting insightsNew Orleans has covered the spread once at home, and is 1-5 overall there this season.The Saints have registered a 5-8-0 record against the spread this season.At home, as 2.5-point underdogs or more, New Orleans is winless ATS (0-4).The Saints are 4-7 ATS when playing as at least 2.5-point underdogs.New Orleans has gone over the total once in six home games this season.Games involving Saints have hit the over four times this year.Saints leadersShough: 1,212 PASS YDS / 173.1 YPG / 65.2% / 5 TD / 5 INT / 28 CAR / 106 RUSH YDS / 2 TDAlvin Kamara: 131 CAR / 471 YDS / 42.8 YPG / 1 TD / 33 REC / 186 YDS / 16.9 YPG / 0 TDDevin Neal: 50 CAR / 178 YDS / 22.3 YPG / 1 TD / 16 REC / 100 YDS / 12.5 YPG / 0 TDChris Olave: 76 REC / 811 YDS / 62.4 YPG / 5 TDJuwan Johnson: 58 REC / 614 YDS / 47.2 YPG / 3 TDDevaughn Vele: 20 REC / 224 YDS / 28 YPG / 2 TDSaints vs Panthers game infoDate: Sunday, December 14, 2025Time: 4:25 p.m. ETCity: New Orleans, LouisianaVenue: Caesars SuperdomeTV channel: FOXLive stream: Watch on Fubo (Regional restrictions may apply)
Watch Carolina Panthers vs. New Orleans Saints on Fubo! (Regional restrictions may apply)