The Houston Texans (8-5) will meet the Arizona Cardinals (3-10) at NRG Stadium on Sunday, Dec. 14 at 1 p.m. ET, and our computer prediction is a double-digit win by the Texans, 31-12.

Texans vs. Cardinals predictionsPick ATS: Texans (-10)Pick OU: Over (42.5)Prediction:
Texans 31 – Cardinals 12Texans vs. Cardinals odds and lines

National Football League odds courtesy of BetMGM. Odds updated Sunday at 1:34 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: Texans (-10)Moneyline: Texans (-549), Cardinals (+400)Total: 42.5 pointsTexans betting statsHouston’s record against the spread is 7-6-0.Out of 13 Houston games so far this season, three have hit the over.Cardinals betting statsAgainst the spread, Arizona is 6-7-0 this year.This season, eight of Arizona’s 13 games have hit the over.The Cardinals have entered the game as underdogs 10 times this season and won once.Texans vs. Cardinals game infoGame day: Sunday, December 14, 2025Game time: 1 p.m. ETTV channel: FOXLocation: Houston, TexasStadium: NRG StadiumTV channel: FOXLive stream: Watch on Fubo! (Regional restrictions may apply)

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