The rollercoaster week of injury news for the Buffalo Bills has finally pulled into the station at Gillette Stadium.

As the Bills prepare for today’s critical 1 p.m. kickoff against the New England Patriots, the final injury reports paint a picture of a team bolstering its trenches while holding its breath for its secondary.

Throughout the week, the narrative has shifted dramatically. Early predictions earlier this week were clouded by fear that top pass rusher Joey Bosa would miss his second straight game. Those fears were alleviated mid-week when experts reversed course following news that key starters were trending toward a return.

However, a late-week practice injury to cornerback Christian Benford has added a fresh layer of tension to a game with massive AFC East implications.

Here is the final breakdown of who is in, who is at risk, and how the betting lines and expert predictions have settled on game day.

The Good News: Trench Reinforcements Arrive

The Bills received the best possible news regarding their line play. DE Joey Bosa (hamstring) and RT Spencer Brown (shoulder) have no injury designations and are set to play.

Getting Bosa back is massive for a defense tasked with slowing down Patriots QB Drake Maye, currently an MVP favorite leading an 11-2 squad. Brown’s return is equally vital for keeping Josh Allen clean in a hostile environment.

“It’s good, yeah, we rolling this Sunday,” Brown told reporters earlier in the week.

The Concern: Secondary in Limbo

While the front seven gets healthy, the back end is sweating. CB Christian Benford is officially listed as Questionable after injuring his toe on Thursday and missing practice on Friday.

Head Coach Sean McDermott noted on Friday that he didn’t believe the injury was long-term, but admitted the team was “still gathering information.” If Benford—who is coming off two interception-fueled games—cannot go, rookie Maxwell Hairston or practice squad elevation Dane Jackson may be forced into the spotlight against Patriots weapons like Stefon Diggs.

LB Terrel Bernard (elbow) and WR Joshua Palmer (ankle) are also listed as questionable. If Bernard sits, veteran Shaq Thompson will continue to anchor the defense.

Updated Bills vs. Patriots odds

Utilize the interactive widget below to see the current spread, over/under, and moneyline odds and probabilities for the Bills-Patriots game at Gillette Stadium.

With the confirmed return of Bosa and Brown countering the uncertainty of Benford, the betting markets have stabilized.

Spread: Bills -1.5 (-105)Moneyline: Bills -118, Patriots +105Total: 49.5 (-110)

This line has seen significant movement. The Bills opened as -4.5 favorites, dipped when Bosa’s status was unknown, and have settled at -1.5 as the market respects New England’s 11-win prowess at home.

All betting odds and predictions are accurate as of publication time on Sunday morning.

Expert prediction: A nail-biter in Foxborough

Using updated data inputs from Sunday morning, the experts at Dimers run 10,000 final simulations.

Winner: The model gives the Bills a 57% chance of winning.Score: The projected final score is Bills 24, Patriots 23.Spread: The model sees a coin flip (50/50) on covering the tight -1.5 spread.Best Bet: The strongest edge on the board is Under 49.5 points (-110), with a 57% probability of hitting.Player props to watch

If you are looking for action beyond the final score, the data favors the ground game and key targets.

Anytime Touchdown Probabilities:

James Cook (BUF): 50.1%TreVeyon Henderson (NE): 44.8%Josh Allen (BUF): 45.3%Stefon Diggs (NE): 34.5%

Projected Stat Leaders:

Passing: Drake Maye (242 yards) edges Josh Allen (231 yards).Rushing: James Cook is projected for 88 yards, dominating the ground projections.

Best Available Betting Promos:

The bottom line

With the AFC East hanging in the balance, today’s matchup is shaping up to be a classic defensive struggle defined by who is available—and who isn’t.

The return of Joey Bosa gives Buffalo the trench advantage they desperately need to pressure Drake Maye, but the late injury to Christian Benford leaves a vulnerable spot in the secondary that the Patriots will likely target early.

While the models favor a tight Bills victory (24-23), the volatility of the secondary suggests the smartest money lies on the Under (49.5). Expect a physical, playoff-atmosphere battle where every possession counts.

Kickoff is set for 1 p.m. EST at Gillette Stadium.

If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net for more information.

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