ZT gives his Fantasy Football rankings for DraftKings main slate of contests for Week 16 of the 2025 NFL season.

In Week 16, DraftKings has a juicy 11-game main slate lined up on Sunday afternoon. Seven of the games kick off at 1:00 p.m. ET in the early wave, with two games at 4:05 p.m. ET and two more at 4:25 p.m. ET. In this cheat sheet, we’ll take a look at the fantasy football rankings for each primary position on that main DraftKings slate.

While there is only one divisional contest on the main slate, there are some fascinating potential playoff previews like the Jaguars taking on the Broncos. The one divisional matchup is important, as well, since the Panthers host the Bucs in a critical NFC South contest. 

The fantasy football rankings in this post are based on what we know coming into the week on Monday, so stay tuned to DK Network for more news throughout the week to see if your lineup should be adjusted at all.

These player rankings are based solely on total output, independent of the players’ salaries. They do not account for value, ownership, ceiling or correlation, which should all be factors in assembling your final roster. They are, however, a great starting point as you start to look ahead or as you compare specific options in a particular position.

To catch up on the top lineup from the Week 15 contest, check out my breakdown of the winning lineup. You can also find full rankings for the week at each position on my author page. The rankings on this page do not include any players from the prime time matchups, which are on separate slates. Each of the position-specific rankings includes all the players for the entire week.

Be sure to set your lineup for all Week 11 contests, highlighted by the NFL $2.5M Fantasy Football Millionaire [$1M to 1st]. 

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Top 15 QB

Josh Allen (at CLE), $7,200

Joe Burrow (at MIA), $6,500

Justin Herbert (at DAL), $6,000

Jared Goff (vs. PIT), $6,300

Dak Prescott (vs. LAC), $6,700

Bo Nix (vs. JAC), $6,100

C.J. Stroud (vs. LV), $5,500

Jacoby Brissett (vs. ATL), $5,300

Trevor Lawrence (at DEN), $5,900

Jaxson Dart (vs. MIN), $5,800

Baker Mayfield (at CAR), $5,700

Bryce Young (vs. TB), $5,100

Tyler Shough (vs. NYJ), $5,400

Kirk Cousins (at ARI), $4,800

J.J. McCarthy (at NYG), $4,900

Top 30 RB

Bijan Robinson (at ARI), $8,700

De’Von Achane (vs. CIN), $8,800

Jahmyr Gibbs (vs. PIT), $8,500

James Cook III (at CLE), $7,700

Chase Brown (at MIA), $6,900

Bucky Irving (at CAR), $6,700

Travis Etienne Jr. (at DEN), $7,000

Quinshon Judkins (vs. BUF), $6,000

RJ Harvey (vs. JAC), $6,200

Javonte Williams (vs. LAC), $6,400

Woody Marks (vs. LV), $6,600 – if healthy

Breece Hall (at NO), $5,900

Omarion Hampton (at DAL), $5,800

Tyrone Tracy Jr. (vs. MIN), $5,700

Ashton Jeanty (at HOU), $5,600

Rico Dowdle (vs. TB), $6,300

Devin Neal (vs. NYJ), $5,500 – if healthy

Aaron Jones Sr. (at NYG), $5,200

Jaylen Warren (at DET), $6,100

Tony Pollard (vs. KC), $5,400

David Montgomery (vs. PIT), $5,000

Chuba Hubbard (vs. TB), $4,800

Isaiah Davis (at NO), $4,400

Michael Carter (vs. ATL), $5,400

Isiah Pacheco (at TEN), $4,800

Devin Singletary (vs. MIN), $4,700

Kimani Vidal (at DAL), $5,300

Tyjae Spears (vs. KC),$4,900

Zonovan “Bam” Knight (vs. ATL), $4,900 – if healthy

Sean Tucker (at CAR), $4,700

Top 30 WR

Ja’Marr Chase (at MIA), $8,600

Amon-Ra St. Brown (vs. PIT), $8,400

CeeDee Lamb (vs. LAC), $7,800

Nico Collins (vs. LV). $7,500

Michael Wilson (vs. ATL), $6,900 – assuming no Marvin Harrison Jr.

George Pickens (vs. LAC), $7,300

Mike Evans (at CAR), $6,300

Rashee Rice (at TEN), $7,400

Chris Olave (vs. NYJ), $6,500

Jaylen Waddle (vs. CIN), $6,800

Tee Higgins (at MIA), $6,600 – if healthy

Tetairoa McMillan (vs. TB), $5,800

DK Metcalf (at DET), $5,400

Courtland Sutton (vs. JAC), $5,700

Justin Jefferson (at NYG), $6,000

Jameson Williams (vs. PIT), $6,400

Ladd McConkey (at DAL), $6,100

Emeka Egbuka (at CAR), $5,900

Wan’Dale Robinson (vs. MIN), $6,200

Jakobi Meyers (at DEN), $5,500

Adonai Mitchell (at NO), $4,500

Quentin Johnston (at DAL), $4,900–if healthy

Keenan Allen (at DAL), $4,800

Brian Thomas Jr. (at DEN), $5,400

Chris Godwin (at CAR), $5,300

Xavier Worthy (at TEN), $4,400

Jalen Coker (vs. TB), $4,400

Khalil Shakir (at CLE), $5,100

Jordan Addison (at NYG), $5,000

Jayden Higgins (vs. LV), $4,100

Top 15 TE

Trey McBride (vs. ATL), $7,600

Kyle Pitts Sr. (at ARI), $5,000

Brock Bowers (at HOU), $5,600

Travis Kelce (at TEN), $4,700

Harold Fannin Jr. (vs. BUF), $4,500

Dalton Schultz (vs LV), $4,200

Dalton Kincaid (at CLE), $4,300

Oronde Gadsden II (at DAL), $4,100

Juwan Johnson (vs. NYJ), $4,000

Jake Ferguson (vs. LAC), $4,400

Mike Gesicki (at MIA), $3,600

Brenton Strange (at DEN), $3,900

Theo Johnson (vs. MIN), $3,700

Mason Taylor (at NO), $3,100– if healthy

Darren Waller (vs. CIN), $3,500