The Los Angeles Chargers (10-4) visit Dallas Sunday with an eye on clinching a playoff berth while the Cowboys (6-7-1) postseason hopes may be extinguished before they even take the field.

Justin Herbert and the Chargers have won six of their last seven games, including a big win last week that eliminated Patrick Mahomes and the Chiefs from playoff contention. They can secure a playoff spot with a victory and a loss or tie by either the Colts or Texans.

If Jalen Hurts and the Eagles win against Washington Saturday, Dak Prescott and the Cowboys will be eliminated from playoff consideration.

Matchup to Watch: Cowboys’ offense vs. Chargers’ Defense

The game pits the Cowboys’ elite passing offense against a Chargers’ defense that has allowed less than 20 points in three straight games and ranks ninth in opposing points per game.

Lets take a deeper dive into this week’s matchup between the Chargers and the Cowboys.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to Watch the Chargers vs. Cowboys live SundayDate: Sunday, December 21, 2025Time: 1:00PM ESTSite: AT&T StadiumCity: Arlington, TXNetwork/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered at NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game Odds: Chargers at Cowboys

The latest odds as of Wednesday courtesy of DraftKings:

Moneyline: Los Angeles Chargers (+114), Dallas Cowboys (-135)Spread: Cowboys -1.5Total: 48.5 points

This game opened at Cowboys -2.0 with the Game Total set at 49.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Los Angeles at DallasChargers Starting QB: Justin Herbert
Last Game: 12/14 at Kansas City – 19-29, 210yds, 1TD, 1INT, Sacked 4 times, 2 carries for 0yds rushing
Season: 14GP, 296-451, 3191yds, 23TDs, 12INTs, Sacked 49 times, 69 carries for 419yds rushingCowboys Starting QB: Dak Prescott
Last Game: 12/14 vs. Minnesota – 23-38, 294yds, 0TDs, 0INTs, Sacked 2 times, 1 carry for 2yds rushing
Season: 14GP, 357-522, 3931yds, 26TDs, 10INTs, Sacked 24 times, 45 carries for 140yds rushing Chargers at Cowboys: Team Stats and Betting TrendsThe OVER has cashed an NFL-leading 10 times in Dallas’ 14 games this season (10-4)The OVER has cashed 6 times in the Chargers’ 14 games this season (6-8)The Chargers are 7-6-1 ATS this seasonThe Cowboys are 7-7 ATS this season

Harbaugh on ACL injuries, Chiefs, Moore, and more

Los Angeles Chargers head coach Jim Harbaugh joins Dan Patrick to discuss the slew of ACL injuries plaguing the NFL in recent years, the Kansas City Chiefs and Patrick Mahomes, Justin Herbert, Sherrone Moore, and more.

Chargers Player InjuriesWR Quentin Johnson (groin) is listed as questionable for Sunday’s gameWR Derius Davis (ankle) is listed as questionable for Sunday’s gameOT Trey Pipkins III (ankle) is listed as questionable for Sunday’s gameS Elijah Molden (hamstring) is listed as questionable for Sunday’s gameS RJ Mickens (shoulder) is listed as questionable for Sunday’s gameCowboys Player InjuriesLT Tyler Guyton (ankle) is listed as questionable for Sunday’s gameFB Hunter Luepke (concussion) is listed as questionable for Sunday’s gameCB Trevon Diggs (knee) remains eligible to be activated from the IROT Ajani Cornelius (knee) is now eligible to be activated from the IRS Juanyeh Thomas (migraines) is now eligible to be activated from the IR
Rotoworld Best Bets

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Chargers and the CowboysMoneyline: Rotoworld Bet is staying away from a play on the Moneyline.Spread: Rotoworld Bet is recommending a play ATS on the Los Angeles Chargers +1.5.Total: Rotoworld Bet is recommending a play on the OVER on the Game Total of 49.0.

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