The Houston Texans (10-5) visit the Los Angeles Chargers (11-4) at SoFi Stadium in Inglewood for a Week 17 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Saturday, December 27, including live updated odds and injury report news.
NameWeek 162025 SeasonBlake Schuster12-3-1127-94-6Jon Hoefling8-7-1117-117-6Tyler Dragon6-9-1116-118-6Chris Bumbaca8-7-1101-104-5Lorenzo ReyesN/A107-112-5Jordan Mendoza11-4-198-107-5Richard Morin10-5-147-34-3Chargers vs. Texans live odds, moneyline, over/under
Opening Lines
Spread: Chargers (-3.5)Moneyline: Chargers (-185), Texans (+154)Over/Under: 43.5
Get the edge with our exclusive NFL betting picks
Chargers vs. Texans picks against the spreadJordan Mendoza: Houston Texans (+2)
The performance against the Raiders should be concerning, but the Chargers are a great opportunity for Houston’s defense to get back on track.
Tyler Dragon: Los Angeles Chargers (-2)
Can the Chargers banged up O-line hold up against the Texans? If they can protect Justin Herbert just a little, they should win at home.
Blake Schuster: Houston Texans (+2)
The Chargers already clinched the playoffs. The Texans have not. Advantage: Houston.
Jon Hoefling: Houston Texans (+2)
The Texans’ defense is too good to allow Harbaugh’s run-focused game plan to control the tempo. Just a bad matchup for Los Angeles.
Lorenzo Reyes: Los Angeles Chargers (-2)
This is a fascinating matchup, but I’m going to give the edge to the Chargers because they’re at home and are more balanced, whereas Houston’s offense is susceptible to the occasional poor performance.
Christopher Bumbaca: Houston Texans (+2)
The Texans’ offense certainly can’t afford many repeat performances like the one they turned in last week against the lowly Las Vegas Raiders. But I think the defense carries them with a playoff berth on the line.
Chargers vs. Texans updated injury reportNFL Week 17 picks, predictions, oddsSuper Bowl 60 updated odds