Two of the hottest teams in the NFL meet Saturday afternoon in Southern California when C.J. Stroud and the Houston Texans (10-5) take on Justin Herbert and the Los Angeles Chargers (11-4) at SoFi Stadium. The Texans have won seven straight and the Chargers four in a row and seven of their last eight.

The stakes are high for each of these teams. With a win the Texans clinch a spot in the playoffs and remain in the hunt for the AFC South title. They trail the Jaguars by a game. The Chargers are in the playoffs. They are one game behind the Broncos in the AFC West. With a win Saturday and a victory in their final regular season game against the Broncos, Los Angeles will win the division crown and could still secure the top overall seed in the AFC playoffs.

Lets take a look at the matchup including a few key stats and trends, the quarterbacks, and those listed on the injury report.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to Watch the Texans and the Chargers live Saturday

Date: Saturday, December 27, 2025Time: 4:30PM ESTSite: SoFi StadiumCity: Inglewood, CANetwork/Streaming: NFL Network

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Game Odds: Texans at Chargers

The latest odds as of Tuesday courtesy of DraftKings:

Moneyline: Houston Texans (+110), Los Angeles Chargers (-130)Spread: Chargers -2.5Total: 39.5 points

This game opened at Texans -1.5 with the Game Total set at 39.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup: Texans at ChargersTexans Starting QB: C.J. Stroud
Last Game: 12/21 vs. Las Vegas – 23-35, 187yds, 1TD, 0INTs, Sacked 0 times, 4 carries for 0yds rushing
Season: 12GP, 243-372, 2628yds, 16TDs, 6INTs, Sacked 23 times, 42 carries for 204yds rushing
Chargers Starting QB: Justin Herbert
Last Game: 12/21 at Dallas – 23-29, 300yds, 2TDs, 0INTs, Sacked 0 times, 8 carries for 42yds rushing
Season: 15GP, 319-480, 3491yds, 25TDs, 12INTs, Sacked 49 times, 77 carries for 461yds rushingTexans at Chargers: Team Stats and Betting TrendsThe Chargers are 8-7 ATS this seasonThe Texans are 8-6-1 ATS this seasonThe OVER has cashed in 6 of the Chargers’ 15 games this season (6-8-1)The OVER has cashed in 5 of the Texans’ 15 games this season (5-9-1)C.J. Stroud has thrown for over 230 yards in just 5 of his 12 startsOmarion Hampton has rushed for at least 61 yards in 4 of his last 6 games including 85 last week against Dallas

Early best bets for Jaguars vs. Colts

Trysta Krick and Drew Dinsick unpack the early bets for the Jacksonville Jaguars’ upcoming Week 17 game against the Indianapolis Colts and reveal their favorite bets.

Texans Player InjuriesRB Woody Marks (ankle) is listed as questionable for Saturday’s gameLT Aireontae Ersery (hand) is listed as questionable for Saturday’s gameRT Trent Brown (knee) is listed as questionable for Saturday’s game LB Jake Hansen (chest) is listed as questionable for Saturday’s gameLB Azeez Al-Shaair (ankle) is listed as questionable for Saturday’s gameChargers Player InjuriesRB Kimani Vidal (neck) is listed as questionable for Saturday’s gameWR Tre’ Harris (finger) is listed as questionable for Saturday’s gameWR Derius Davis (ankle) is listed as questionable for Saturday’s gameLT Jamaree Salyer (hamstring) is listed as questionable for Saturday’s gameOT Trey Pipkins III (ankle) is listed as questionable for Saturday’s gameLB Bud Dupree (back) is listed as questionable for Saturday’s gameCB Donte Jackson (groin) is listed as questionable for Saturday’s gameS R.J. Mickens (shoulder) is listed as questionable for Saturday’s gameCB Benjamin St-Juste (shoulder) is listed as questionable for Saturday’s gameLB Denzel Perryman (susp.) received a 2-game suspension for violating the rules intended to protect the health and safety of playersRotoworld Best Bets

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Texans and the ChargersMoneyline: Rotoworld Bet is leaning towards a play on the Texans (+110) on the Moneyline.Spread: Rotoworld Bet is leaning towards a play on the Texans +2.5.Total: Rotoworld Bet is recommending a play on the Game Total OVER 39.5.

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Jay Croucher (@croucherJD)Drew Dinsick (@whale_capper)Vaughn Dalzell (@VmoneySports)Trysta Krick (@Trysta_Krick)