The Los Angeles Chargers are 2-point favorites over the Houston Texans in Week 17 of the 2025 regular season. The over/under is 39.5 points, per BetMGM Sportsbook.

That means oddsmakers are taking bets on whether the two teams will combine to score more than or fewer than 39.5 points.

My score prediction for the game is a 21-17 Bolts win, with a combined total of 38 points. So, if I were putting money based on my prediction, I’d bet the Under.

As for game picks, analysts are leaning toward L.A. winning.

Nate Davis (USA Today): Texans

Jarrett Bell (USA Today): Chargers

Mike Clay (ESPN): Chargers

Matt Bowen (ESPN): Texans

Pete Prisco (CBS Sports): Chargers

Bill Bender (Sporting News): Chargers

NFL.com Staff: Texans (3-2)

Bleacher Report: Chargers (4-3)

Saturday’s game will begin at 1:00 p.m. PT and will be televised on NFL Network.