Christian McCaffrey and the San Francisco 49ers (11-4) meet the Chicago Bears (11-4) on Sunday at 8:20 p.m. ET at Levi’s Stadium.

In their most recent outing, the 49ers took down the Indianapolis Colts 48-27. The Bears are coming off of a victory over the Green Bay Packers by the score of 22-16. Against the Colts, Brock Purdy led the Niners with 295 yards on 25-of-34 passing (73.5%) for five touchdowns and one interception. McCaffrey carried the ball 21 times for 117 yards (5.6 yards per carry). He added six receptions for 29 yards and two touchdowns. George Kittle had seven receptions for 115 yards (16.4 per catch) and one touchdown against the Colts. Caleb Williams’ showing for the Bears against the Packers included 19-of-34 passing for 250 yards, two touchdowns and no interceptions. He rushed three times for 30 yards. D’Andre Swift carried the ball 13 times for 58 yards. He caught two passes for 12 yards. D.J. Moore caught five passes for 97 yards (19.4 yards per catch), scoring one touchdown.

We provide more details below, including how to watch this game on Fubo.

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49ers vs. Bears game infoGame day: Sunday, December 28, 2025Game time: 8:20 p.m. ETLocation: Santa Clara, CaliforniaStadium: Levi’s StadiumTV channel: NBC/PeacockLive stream: Fubo (Watch Now!)

Watch San Francisco 49ers vs. Chicago Bears on Fubo! (Regional restrictions may apply)

49ers vs. Bears betting info

NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 3:05 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: 49ers (-3)Moneyline: 49ers (-165), Bears (+140)Total: 52.5 points

Watch San Francisco 49ers vs. Chicago Bears on Fubo! (Regional restrictions may apply)