SANTA CLARA — Tight end George Kittle stayed off the practice field all week since Monday night’s low-ankle sprain, but the 49ers aren’t ready to rule him out of Sunday night’s game.

Kittle, along with wide receiver Ricky Pearsall, is questionable for when the 49ers (11-4) host the NFC North-leading Bears (11-4). Official moves are not due until 90 minutes before the 5:20 p.m. kickoff at Levi’s Stadium.

“George told me he’d have a much better idea (Saturday). Hopefully we’ll know then,” coach Kyle Shanahan said after Friday’s practice.

Kittle battled through pain and gathered seven receptions for 115 yards before watching the 49ers wrap up a 48-27 win over the Indianapolis Colts. He produced 151 yards on six catches last December when the 49ers beat the visiting Bears 38-13.

The 49ers went 3-2 without Kittle after his hamstring tear in the season opener at Seattle.

PEARSALL RETURN?

Pearsall was limited in practice after missing Monday night’s game because of a right-knee injury. He originally got hurt in a Sept. 28 loss to Jacksonville, missed the next six games, then aggravated his knee late in a Dec. 14 against Tennessee.

In the eight games he’s played, Pearsall have averaged 14.3 yards per catch, totaling 31 receptions for 443 yards and no touchdowns. He had 31 catches for 400 yards and three touchdowns in 11 games last season.

DEFENSIVE HEALTH

Cornerback Renardo Green (neck) is improving but out a second straight game, likely leading to another start for Darrell Luter Jr.

The 49ers’ defense is tracking toward better health to face the NFL’s second-best rushing attack. Linebacker Tatum Bethune (ankle) and defensive linemen Sam Okuayinonu (ankle) and Yetur Gross-Matos (hamstring) all were limited in practice.

BEARS INJURIES

Wide receiver Rome Odunze (foot) will miss his fourth straight game, and also ruled out is cornerback Nick McCloud.

Questionable are middle linebacker T.J. Edwards (glute); cornerbacks Nahason Wright (hamstring/illness), C.J. Gardner-Johnson (knee) and Josh Blackwell (illness); and guard Luke Newman, who’s on Injured Reserve.