In the matchup between the Seattle Seahawks and Carolina Panthers on Sunday, Dec. 28 at 1 p.m. ET, our projection model expects the Seahawks to emerge victorious. Seeking predictions on the final score, spread, and point total, too? Find a complete game projection below.

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Seahawks vs. Panthers Game Info and TV Channel

When: Sunday, December 28, 2025 at 1 p.m. ET
Where: Bank of America Stadium in Charlotte, North Carolina
TV: CBS
Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)

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Listen to the game on 99.7 The Fox

Seahawks vs. Panthers Odds and Betting Info

Spread favorite: Seahawks (-7)
Moneyline: Seahawks (-357), Panthers (+284)
Total: 42.5 points
Seahawks vs. Panthers Prediction

Pick ATS: Seahawks (-7)

Pick OU: Over (42.5)

Prediction:

Seahawks 29 – Panthers 16

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Seahawks vs. Panthers Betting Insights

The Seahawks have won 10 games against the spread this season, while failing to cover five times.
The Panthers have won nine games against the spread this year, failing to cover six times.
When playing as at least 7-point favorites this season, the Seahawks have an ATS record of 3-2.
When playing as at least 7-point underdogs this season, Carolina has an ATS record of 3-2.
The Seahawks and their opponent have combined to go over the point total nine out of 15 times this season.
In 2025, seven Panthers games have hit the over.

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