The San Francisco 49ers (11-4) take a five-game winning streak into their contest with the Chicago Bears on Sunday, December 28, 2025 at Levi’s Stadium. The 49ers are listed as favorites in this one, with the spread sitting at 3 points. The over/under in the contest is set at 52.5 points.
The Bears’ most recent contest was versus the Green Bay Packers, and they won by a score of 22-16.
In that game versus the Packers, Bears quarterback Caleb Williams completed 19 of 34 passes for 250 yards, with two touchdowns and no interceptions.
The 49ers’ most recent contest was versus the Indianapolis Colts, and they won by a score of 48-27.
Bears vs 49ers betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 10:07 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: San Francisco (-3)Moneyline: San Francisco (-182), Chicago (+153)Total: 52.5 pointsBears betting insightsChicago is 5-3 overall, and 5-3 against the spread, away from home.The Bears have compiled a 10-5-0 record against the spread this season.On the road, Chicago has two wins ATS (2-2) as 3-point underdogs or more.The Bears have an ATS record of 2-2 when playing as at least 3-point underdogs.Chicago has gone over the total in five of eight away games this season.This year, seven Bears games have gone over the point total.Bears leadersWilliams: 3,400 PASS YDS / 226.7 YPG / 57.8% / 23 TD / 6 INT / 71 CAR / 369 RUSH YDS / 3 TDD’Andre Swift: 204 CAR / 993 YDS / 70.9 YPG / 7 TD / 31 REC / 266 YDS / 19.0 YPG / 1 TDKyle Monangai: 155 CAR / 731 YDS / 48.7 YPG / 5 TD / 14 REC / 140 YDS / 9.3 YPG / 0 TDD.J. Moore: 48 REC / 664 YDS / 44.3 YPG / 6 TDRome Odunze: 44 REC / 661 YDS / 55.1 YPG / 6 TDColston Loveland: 42 REC / 528 YDS / 37.7 YPG / 4 TDBears vs 49ers game infoDate: Sunday, December 28, 2025Time: 8:20 p.m. ETCity: Santa Clara, CaliforniaVenue: Levi’s StadiumTV channel: NBC/PeacockLive stream: Watch on Fubo (Regional restrictions may apply)
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