What to KnowProgramming note: Before the 49ers play the Chicago Bears on “Sunday Night Football” at Levi’s Stadium, tune into “49ers Pregame Live” at 4 p.m. PT on NBC Sports Bay Area or stream the show in the NBC Sports app for a full game preview with Carlos Ramirez, Rod Brooks and Matt Maiocco.San Francisco and Chicago enter a prime-time Week 17 matchup with identical 11-4 records and each still in the hunt for the No. 1 NFC playoff seed.Christian McCaffrey officially is on 1,000-1,000 watch after surpassing the rushing mark in San Francisco’s Week 16 win. The star 49ers running back has 1,039 rushing yards and 849 receiving yards with two regular-season games remaining.Tight end George Kittle, who missed practice all week but was listed as questionable, officially was ruled out of Sunday’s game with an ankle injury. Ricky Pearsall is cleared to play.Insider Matt Maiocco listed his five 49ers players to watch in San Francisco’s penultimate game of the 2025 NFL season.Programming note: Immediately after the Week 16 game ends, watch “49ers Postgame Live” on NBC Sports Bay Area or stream the show in the NBC Sports app for full reaction, analysis and interviews.
Follow this live blog for the latest score updates, game highlights, news and analysis from Levi’s Stadium in Santa Clara: