The Indianapolis Colts (8-8) visit the Houston Texans (11-5) at NRG Stadium in Houston for a Week 18 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, January 4, including live updated odds and injury report news.
NameWeek 172025 SeasonBlake Schuster3-12-1130-106-7Jon Hoefling9-6-1126-123-7Tyler Dragon6-9-1122-127-7Chris Bumbaca7-8-1108-112-6Lorenzo Reyes4-11-1111-123-6Jordan Mendoza7-8-1105-115-6Richard MorinN/A47-34-3Texans vs. Colts live odds, moneyline, over/under
Opening Lines
Spread: Texans (-4.5)Moneyline: Texans (-218), Colts (+180)Over/Under: 40.5
Get the edge with our exclusive NFL betting picks
Texans vs. Colts picks against the spreadJon Hoefling: Houston Texans (-10.5)
Not starting Philip Rivers is all I needed to hear. Blowout incoming.
Tyler Dragon: Houston Texans (-10.5)
The Texans are the hottest team in the NFL.
Christopher Bumbaca: Indianapolis Colts (+10.5)
Let Riley Leonard rip it. The Houston defense is scary but the Texans have their eyes set on the postseason.
Jordan Mendoza: Indianapolis Colts (+10.5)
What a disappointing end for Indianapolis. Houston still has something to play for and while it does pick up the victory, the Colts make the Texans work every second for it.
Lorenzo Reyes: Houston Texans (-10.5)
Houston’s defense is elite and Indianapolis is starting Riley Leonard. I expect the Colts to struggle to put up points.
Blake Schuster: Indianapolis Colts (+10.5)
The Colts have been feisty and I just don’t think we’re going to see Houston’s starters play the whole game.
Texans vs. Colts updated injury reportNFL Week 18 picks, predictions, oddsSuper Bowl 60 updated odds