The Arizona Cardinals (3-13) bring an eight-game losing streak into a matchup against the Los Angeles Rams (11-5) on Sunday, January 4, 2026 at SoFi Stadium. Los Angeles is a 7.5-point favorite in the game.

Rams vs. Cardinals game infoGame day: Sunday, January 4, 2026Game time: 4:25 p.m. ETTV channel: FOXLocation: Inglewood, CaliforniaStadium: SoFi StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)

Watch Los Angeles Rams vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)

Rams vs. Cardinals odds & betting linesSpread favorite: Los Angeles (-7.5)Moneyline: Los Angeles (-345), Arizona (+272)Total: 46.5 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Rams vs. Cardinals recent matchupsLos Angeles has gone 4-1 versus Arizona over the last five matchups between the two teams.In those games versus the Cardinals, the Rams have gone 3-2 against the spread, with those games outpacing the total on three occasions.Los Angeles scored 131 points in those five matchups, with Arizona putting up 90.Rams vs. Cardinals betting insightsLos Angeles is 11-5-0 against the spread in 16 opportunities this season. The Rams have been named the moneyline favorite 14 times this season, and they have recorded an 11-3 record in those contests. Arizona has a 6-10-0 record against the spread so far this season. This will be the 14th time this year the Cardinals are the moneyline underdog. They are 1-12 in games as an underdog.Rams scoring insightsThe Rams put up 27.7 points per game at home, which is worse than their 31.9 average on the road.Defensively, Los Angeles allows fewer points at home (17.9 per game) than on the road (22.3).The Rams have put up 33.6 points per game in the division, which is better than their average against the rest of the league of 28.5.Los Angeles is allowing 25.2 points per game in divisional contests, which is worse than its 18.2 average in non-division games.From an offensive standpoint, the Rams have been a top-five unit over the last three games with 34.0 points per game (third-best). They haven’t fared as well on the other side of the ball, with 33.0 points allowed per game (third-worst) over that stretch.Cardinals scoring insightsAt home, the Cardinals are averaging more points (21.6) than away (20.3).On defense, Arizona concedes more points at home (29.1 per game) than away (27.3).On offense, the Cardinals are putting up 19.2 points per game in divisional contests, which is less than their 21.7 average in non-division games.Arizona averages more points conceded in division games (33.8) than outside the division (25.6).In their past three games, the Cardinals are putting up 17.7 points per game (27th in NFL) and giving up 34.3 per game (second-worst).Rams injury reportRams:
Tyler Higbee: Full Participation in Practice (Ankle),
Kyren Williams: Limited Participation in Practice (Ankle),
Omar Speights: Limited Participation in Practice (Ankle),
Xavier Smith: Full Participation in Practice (Chest),
Jaylen McCollough: Limited Participation in Practice (Hip),
AJ Jackson: Limited Participation in Practice (Knee),
Braden Fiske: Limited Participation in Practice (Ankle),
Josh Wallace: Did Not Participate In Practice (Ankle),
Kevin Dotson: Did Not Participate In Practice (Ankle),
Blake Corum: Did Not Participate In Practice (Ankle),
Davante Adams: Limited Participation in Practice (Hamstring)Cardinals injury reportCardinals:
Max Melton: Full Participation in Practice (Heel),
Will Johnson: Full Participation in Practice (Thumb),
Hjalte Froholdt: Full Participation in Practice (Elbow),
Budda Baker: Full Participation in Practice (Concussion),
Josh Sweat: Did Not Participate In Practice (Ankle),
Marvin Harrison Jr.: Did Not Participate In Practice (Foot),
Kitan Crawford: Did Not Participate In Practice (Ankle),
Evan Brown: Did Not Participate In Practice (NIR – Personal),
Kelvin Beachum: Limited Participation in Practice (Nir – Rest)

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