NFL Overreactions Week 17
USAT’s Prince Grimes breaks down the best games of NFL Week 17 and the unfolding playoff picture.
Sports Seriously
Who will win Saturday’s second NFL game in NFL Week 18?
The Seattle Seahawks and San Francisco 49ers play on Saturday, Jan. 3, at the 49ers’ Levi’s Stadium in a game on the NFL Week 18 schedule.
What do NFL Week 18 odds say about the game? Who are NFL Week 18 predictions and NFL Week 18 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 18 win probabilities?
Check out The Arizona Republic’s score prediction for the game, as well as Seahawks vs 49ers picks, odds and win chances for the Jan. 3 NFL Week 18 game, which can be seen at 6 p.m. MST on ESPN (stream on FUBO).
NFL Week 18 picks: Panthers at Buccaneers | Seahawks at 49ers | Saints at Falcons | Browns at Bengals | Colts at Texans | Titans at Jaguars | Packers at Vikings | Cowboys at Giants | Jets at Bills | Lions at Bears | Chargers at Broncos | Cardinals at Rams | Chiefs at Raiders | Dolphins at Patriots | Commanders at Eagles | Ravens at Steelers | The Republic’s score predictions
Watch Seahawks at 49ers game on FUBO (free trial)
NFL Saturday prediction for Seahawks vs 49ers game
The Arizona Republic is predicting a 20-17 win for the 49ers over the Seahawks in the NFL Week 18 football game.
Jeremy Cluff writes: “These teams met in Week 1 of the season in Seattle, with San Francisco getting a 17-13 win. They fittingly get to meet in the final week of the season. We expect a similar score, with a close 49ers win over the Seahawks.”
NFL Saturday picks for 49ers vs Seahawks game
Will the Seahawks or 49ers win the game in NFL Week 18?
Sports Betting Dime’s formula predicts a 7-point win for the Seahawks over the 49ers today.
Sportsbook Review says to bet the 49ers on the moneyline against the Seahawks on Saturday.
Sportsnaut’s final score prediction for the NFL Week 18 game? Seattle Seahawks 20, San Francisco 49ers 17.
NFL Saturday win probabilities for Seahawks vs 49ers game
The 49ers have a 50.7% chance to beat the Seahawks on Saturday, according to ESPN.
The site gives the Seahawks a 48.9% shot at winning the NFL Week 18 game, with the remaining percentage accounting for a tie.
NFL Saturday odds for 49ers vs Seahawks game
The 49ers are a 1.5-point favorite over the Seahawks in NFL Week 18 odds for the game, courtesy of BetMGM Sportsbook.
San Francisco is -110 on the moneyline, while Seattle is -110.
The over/under (point total) is set at 49.5 points.
NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don’t miss a thing.