Updated Jan. 16, 2026, 10:12 p.m. PT
In this season’s Divisional Round of the NFC playoffs, the Seattle Seahawks are significant favorites (-7) over the San Francisco 49ers. Lumen Field in Seattle, Washington will act as host on January 17, 2026, starting at 8 p.m. ETand airing on FOX. The over/under is set at 45 in the contest.
The Seahawks will be facing the 49ers for the second time in a row, with the Seattle Seahawks taking the previous matchup on January 3, 2026, .
In that game versus the 49ers, Hawks quarterback Sam Darnold completed 20 of 26 attempts for 198 yards, with no touchdowns and no interceptions.
Against the Philadelphia Eagles in their most recent contest, the 49ers won 23-19.
Seahawks vs 49ers betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 1:12 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Expert NFL picks: Exclusive betting insights only at USA TODAY.Spread favorite: Seattle (-7)Moneyline: Seattle (-339), San Francisco (+272)Total: 45 pointsSeahawks betting insightsSeattle is 4-4 against the spread, and 6-2 overall, at home this year.The Seahawks have registered a 12-5-0 record against the spread this season.At home, as 7-point favorites or greater, Seattle is 3-1 ATS.The Seahawks are 3-2 ATS when playing as at least 7-point favorites.This year, Seattle has gone over the total in five of eight games at home.Seahawks games have finished with a final combined score above the over/under nine times this season.Seahawks leadersDarnold: 4,048 PASS YDS / 238.1 YPG / 67.7% / 25 TD / 14 INTKenneth Walker III: 221 CAR / 1,027 YDS / 60.4 YPG / 5 TD / 31 REC / 282 YDS / 16.6 YPG / 0 TDZach Charbonnet: 184 CAR / 730 YDS / 45.6 YPG / 12 TD / 20 REC / 144 YDS / 9.0 YPG / 0 TDJaxon Smith-Njigba: 119 REC / 1,793 YDS / 105.5 YPG / 10 TDRashid Shaheed: 59 REC / 687 YDS / 38.2 YPG / 2 TDCooper Kupp: 47 REC / 593 YDS / 37.1 YPG / 2 TDSeahawks vs 49ers game infoDate: Saturday, January 17, 2026Time: 8 p.m. ETCity: Seattle, WashingtonVenue: Lumen FieldTV channel: FOXLive stream: Watch on Fubo (Regional restrictions may apply)Watch Seattle Seahawks vs. San Francisco 49ers on Fubo! (Regional restrictions may apply)
Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.
Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose.  While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling.  We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site.  Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.